Copula Gaussian graphical models with penalized ascent Monte Carlo EM algorithm

被引:12
作者
Abegaz, Fentaw [1 ]
Wit, Ernst [1 ]
机构
[1] Univ Groningen, Johann Bernoulli Inst Math & Comp Sci, NL-9747 AG Groningen, Netherlands
关键词
Gaussian copula; (l)-penalized maximum likelihood; Gaussian graphical models; ascent-MCEM algorithm; extended rank likelihood; conditional independence; BREAST-CANCER; MAXIMUM-LIKELIHOOD; BCL-2; EXPRESSION; AMPLIFICATION; CONVERGENCE; ASSOCIATION; SELECTION; THERAPY; GENE;
D O I
10.1111/stan.12066
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Typical data that arise from surveys, experiments, and observational studies include continuous and discrete variables. In this article, we study the interdependence among a mixed (continuous, count, ordered categorical, and binary) set of variables via graphical models. We propose an (1)-penalized extended rank likelihood with an ascent Monte Carlo expectation maximization approach for the copula Gaussian graphical models and establish near conditional independence relations and zero elements of a precision matrix. In particular, we focus on high-dimensional inference where the number of observations are in the same order or less than the number of variables under consideration. To illustrate how to infer networks for mixed variables through conditional independence, we consider two datasets: one in the area of sports and the other concerning breast cancer.
引用
收藏
页码:419 / 441
页数:23
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