Prevalence of activating thyrotropin receptor and Gsα gene mutations in paediatric thyroid toxic adenomas: a multicentric Italian study

被引：4

作者：

Agretti, P. ^{[1
]}

Segni, M. ^{[2
]}

De Marco, G. ^{[1
]}

Ferrarini, E. ^{[1
]}

Di Cosmo, C. ^{[1
]}

Corrias, A. ^{[3
]}

Weber, G. ^{[4
]}

Larizza, D. ^{[5
]}

Calcaterra, V. ^{[5
]}

Pelizzo, M. R. ^{[6
]}

Cesaretti, G. ^{[7
]}

Vitti, P. ^{[1
]}

Tonacchera, M. ^{[1
]}

机构：

[1] Univ Pisa, Univ Hosp Pisa, Sect Endocrinol, Dept Clin & Expt Med, Pisa, Italy

[2] Univ Roma La Sapienza, Dept Paediat, Rome, Italy

[3] Univ Turin, Regina Margherita Hosp, Dept Paediat Endocrinol, Turin, Italy

[4] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Dept Paediat, Milan, Italy

[5] Univ Pavia, IRCCS Policlin S Matteo Fdn, Dept Paediat Sci, I-27100 Pavia, Italy

[6] Univ Padua, Inst Med & Surg Sci, Dept Surg Pathol, Padua, Italy

[7] Univ Pisa, Univ Hosp Pisa, Sect Paediat, Dept Clin & Expt Med, Pisa, Italy

来源：

CLINICAL ENDOCRINOLOGY | 2013年 / 79卷 / 05期

关键词：

STIMULATING HORMONE-RECEPTOR;

D O I：

10.1111/cen.12158

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：747 / 749

页数：3

共 5 条

[1] A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism [J].

DeRoux, N ;

Polak, M ;

Couet, J ;

Leger, J ;

Czernichow, P ;

Milgrom, E ;

Misrahi, M .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (06) :2023-2026

[2] Contacts between extracellular loop two and transmembrane helix six determine basal activity of the thyroid-stimulating hormone receptor [J].

Kleinau, Gunnar ;

Claus, Maren ;

Jaeschke, Holger ;

Mueller, Sandra ;

Neumann, Susanne ;

Paschke, Ralf ;

Krause, Gerd .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (01) :518-525

[3] INCIDENCE OF JUVENILE THYROTOXICOSIS IN DENMARK, 1982-1988 - A NATIONWIDE STUDY [J].

LAVARD, L ;

RANLOV, I ;

PERRILD, H ;

ANDERSEN, O ;

JACOBSEN, BB .

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1994, 130 (06) :565-568

[4] SOMATIC MUTATIONS CAUSING CONSTITUTIVE ACTIVITY OF THE THYROTROPIN RECEPTOR ARE THE MAJOR CAUSE OF HYPERFUNCTIONING THYROID ADENOMAS - IDENTIFICATION OF ADDITIONAL MUTATIONS ACTIVATING BOTH THE CYCLIC ADENOSINE-3',5'-MONOPHOSPHATE AND INOSITOL PHOSPHATE-CA2+ CASCADES [J].

PARMA, J ;

VANSANDE, J ;

SWILLENS, S ;

TONACCHERA, M ;

DUMONT, J ;

VASSART, G .

MOLECULAR ENDOCRINOLOGY, 1995, 9 (06) :725-733

[5] Autonomous Thyroid Adenoma: Only an Adulthood Disease? [J].

Schwab, Karl Otfried ;

Pfarr, Nicole ;

van der Werf-Grohmann, Natascha ;

Pohl, Martin ;

Raedecke, Jochen ;

Musholt, Thomas ;

Pohlenz, Joachim .

JOURNAL OF PEDIATRICS, 2009, 154 (06) :931-933

← 1 →