Bifunctional Reactivity of CuI: Sequential Ring Opening/N-Arylation

被引：36

作者：

Martins, Andrew ^{[1
]}

Lemouzy, Sebastien ^{[1
]}

Lautens, Mark ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Res Labs, Toronto, ON M5S 3H6, Canada

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 01期

关键词：

PALLADIUM-CATALYZED REACTIONS; MESO BICYCLIC HYDRAZINES; STEREOSELECTIVE-SYNTHESIS; FACILE SYNTHESIS; BOND FORMATION; N-ARYLATION; ONE-POT; CYCLOPENTENES; DESYMMETRIZATION; DIAZABICYCLES;

D O I：

10.1021/ol802357e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sequential use of a single Cut catalyst enables the one-pot synthesis of N-arylaminooxazolidinones through a Lewis acid catalyzed rearrangement followed by an N-arylation reaction. Contrary to previous reports, the formation of a cis-fused 5,5-membered ring system occurs during the rearrangement, as proven by X-ray crystallography.

引用

页码：181 / 183

页数：3

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