How many patients complete an adequate trial of donepezil?

被引：33
作者：
Roe, CM
Anderson, MJ
Spivack, B
机构：
[1] Express Scripts Inc, Outcomes Res, Maryland Hts, MO 63043 USA
[2] Express Scripts Inc, Clin Serv, Maryland Hts, MO 63043 USA
[3] Univ Minnesota, Coll Pharm, Dept Expt & Clin Pharmacol, Minneapolis, MN 55455 USA
[4] Stamford Hlth Syst, Stamford, CT USA
来源：
ALZHEIMER DISEASE & ASSOCIATED DISORDERS | 2002年 / 16卷 / 01期
关键词：
cognitive disorders; dementia; donepezil; medication adherence;
D O I：
10.1097/00002093-200201000-00008
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Pharmacy claims data were used to evaluate medication adherence among 59 new users of donepezil aged 65 to 94 years. The probability (+/-95% confidence interval) of a new user continuing donepezil at 90 days was .797+/-.103 and at 180 days was .627+/-.124. Additionally, 13.9% of those who continued therapy for at least 180 days showed gaps in treatment of six weeks or more. These results suggest that adherence with donepezil could be improved in clinical practice.
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收藏
页码：49 / 51
页数：3
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