Gold nanoparticle-based sensing of "spectroscopically silent" heavy metal ions

被引:845
作者
Kim, YJ
Johnson, RC
Hupp, JT [1 ]
机构
[1] Northwestern Univ, Mat Res Ctr, Dept Chem, Evanston, IL 60208 USA
[2] Northwestern Univ, Ctr Nanofabricat & Mol Self Assembly, Evanston, IL 60208 USA
关键词
D O I
10.1021/nl0100116
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple colorimetric technique for the detection of small concentrations of aqueous heavy metal ions, including toxic metals such as lead, cadmium, and mercury, is described. Functionalized gold nanoparticles are aggregated in solution in the presence of divalent metal ions by an ion-templated chelation process; this causes an easily measurable change in the absorption spectrum of the particles. The aggregation also enhances the hyper-Rayleigh scattering (HRS) response from the nanoparticle solutions, providing an inherently more sensitive method of detection. The chelation/aggregation process is reversible via addition of a strong metal ion chelator such as EDTA. Suggestions for improving the sensitivity and selectivity of the technique are given.
引用
收藏
页码:165 / 167
页数:3
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