Case study and review: Treatment of tricuspid prosthetic valve thrombosis

被引：9

作者：

Zhang, David Yi ^{[2
]}

Lozier, Jay ^{[3
]}

Chang, Richard ^{[4
]}

Sachdev, Vandana ^{[1
]}

Chen, Marcus Y. ^{[1
]}

Audibert, Jennifer L. ^{[1
]}

Horvath, Keith A. ^{[5
]}

Rosing, Douglas R. ^{[1
]}

机构：

[1] NHLBI, Cardiovasc & Pulm Branch, NIH, Bethesda, MD 20892 USA

[2] Univ Miami, Miller Sch Med, Div Internal Med, Miami, FL 33136 USA

[3] NIH, Hematol Serv, Ctr Clin, Bethesda, MD 20892 USA

[4] NIH, Dept Diagnost Radiol, Ctr Clin, Bethesda, MD 20892 USA

[5] NHLBI, Off Director, NIH, Bethesda, MD 20892 USA

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2012年 / 162卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Tricuspid valve; Prosthetic valve; Thrombosis; thrombolysis; fibrinolysis; Ebstein anomaly; Recombinant tissue plasminogen activator (tPa); Pannus; VALVULAR HEART-DISEASE; PLASMINOGEN-ACTIVATOR; MECHANICAL VALVE; TASK-FORCE; THROMBOLYSIS; MANAGEMENT; THERAPY; OBSTRUCTION; GUIDELINES; REPLACEMENT;

D O I：

10.1016/j.ijcard.2011.09.081

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Prosthetic valve thrombosis (PVT) is a severe and life-threatening complication of heart valve replacement. Conventional therapy is surgical thrombectomy or valve replacement. Medical thrombolysis is another emerging option. We report the case of a 57 year old woman with a history of Ebstein anomaly who underwent successful treatment of tricuspid prosthetic valve thrombosis with intra-atrial infusion of very low dose recombinant tissue plasminogen activator (tPA). We review the presentation, etiology, diagnosis, and treatment of tricuspid PVT emphasizing a modified medical option as a safe, minimally invasive alternative to surgical intervention or conventional medical therapy for tricuspid valve thrombosis. Published by Elsevier Ireland Ltd.

引用

页码：14 / 19

页数：6

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