Pregnancy and melanoma

被引：34

作者：

Driscoll, Marcia S. ^{[1
]}

Martires, Kathryn ^{[2
]}

Bieber, Amy Kalowitz ^{[2
]}

Pomeranz, Miriam Keltz ^{[2
]}

Grant-Kels, Jane M. ^{[3
]}

Stein, Jennifer A. ^{[2
]}

机构：

[1] Univ Maryland, Sch Med, Dept Dermatol, Baltimore, MD 21201 USA

[2] NYU, Sch Med, Ronald O Perelman Dept Dermatol, 240 E 38th St,11th Fl, New York, NY 10016 USA

[3] Univ Connecticut, Dept Dermatol, Farmington, CT USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2016年 / 75卷 / 04期

关键词：

hormone replacement therapy; melanoma; oral contraceptives; pregnancy; prognosis; review; ORAL-CONTRACEPTIVE USE; MALIGNANT-MELANOMA; CUTANEOUS MELANOMA; HORMONE-RECEPTORS; WOMEN; EXPRESSION; CANCER; MORTALITY; RISK;

D O I：

10.1016/j.jaad.2016.01.061

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Malignant melanoma is the most common malignancy during pregnancy, and is diagnosed during childbearing age in approximately one-third of women diagnosed with melanoma. The impact of hormonal changes during pregnancy and from iatrogenic hormones on melanoma is controversial. Women undergo immunologic changes during pregnancy that may decrease tumor surveillance. In addition, hormone receptors are found on some melanomas. In spite of these observations, the preponderance of evidence does not support a poorer prognosis for pregnancy-associated melanomas. There is also a lack of evidence that oral contraceptives or hormone replacement therapy worsens melanoma prognosis.

引用

页码：669 / U98

页数：13

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