A new diphenyl ether from marine-derived fungus Aspergillus sp B-F-2

被引：45

作者：

Liu, Rui

Zhu, Weiming

Zhang, Yapeng

Zhu, Tianjiao

Liu, Hongbing

Fang, Yuchun

Gu, Qianqun ^{[1
]}

机构：

[1] Chinese Minist Educ, Lab Marine Drugs, Qingdao 266003, Peoples R China

[2] Ocean Univ China, Inst Marine Drugs & Food, Qingdao 266003, Peoples R China

来源：

JOURNAL OF ANTIBIOTICS | 2006年 / 59卷 / 06期

关键词：

Aspergillus sp; diphenyl ether; asterric acid; anthraquinone; cytotoxicity;

D O I：

10.1038/ja.2006.52

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new diphenyl ether dimethyl 2,3 ' dimethylosoate (1) together with three known compounds monomethylsulochrin (2), emodin (3), and questin (4) were isolated through bioassay-guided fractionations from the culture of a marine-derived fungus Aspergillus sp. B-F-2. The structures of these compounds were determined by spectroscopic methods. Cytotoxicities of compounds 1 and 2 against K562 cell line were preliminarily evaluated by the MTT method and flow cytometry.

引用

页码：362 / 365

页数：4

共 8 条

[1] PURIFICATION AND CHARACTERIZATION OF EMODINANTHRONE OXYGENASE FROM ASPERGILLUS-TERREUS [J].