Effect of Highly Mineralized Natural Water on Redox Processes in HaCaT Keratinocytes

被引：0

作者：

Zaitseva, N. S. ^{[1
]}

Chechushkov, A. V. ^{[1
]}

Kozhin, P. M. ^{[1
]}

Lemza, A. E. ^{[1
]}

Tkachev, V. O. ^{[1
]}

Solomatina, M. V. ^{[1
]}

Starostenko, V. A. ^{[1
]}

机构：

[1] Russian Acad Med Sci, Res Ctr Clin & Expt Med, Siberian Div, Novosibirsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2014年 / 156卷 / 06期

关键词：

HaCaT keratinocytes; hyperosmotic stress; oxidative stress; ROS production; transmembrane mitochondrial potential; REACTIVE OXYGEN;

D O I：

10.1007/s10517-014-2457-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied ROS production by HaCaT keratinocytes, the state of transmembrane mitochondrial potential, and activation of transcription factor Nrf2 in response to brine exposure. It was demonstrated that this exposure induces rapid but moderate decrease in mitochondrial potential, stimulates ROS production, and leads to activation of transcription factor Nrf2.

引用

页码：810 / 812

页数：3

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