Stem Cells in the Cornea

被引：27

作者：

Hertsenberg, Andrew J. ^{[1
]}

Funderburgh, James L. ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Ophthalmol, Pittsburgh, PA 15260 USA

来源：

MOLECULAR BIOLOGY OF EYE DISEASE | 2015年 / 134卷

关键词：

IN-VITRO; PROGENITOR CELLS; N-CADHERIN; LIMBO-KERATOPLASTY; MESENCHYMAL CELLS; EPITHELIAL-CELLS; STROMAL TISSUE; EXPRESSION; MATRIX; GROWTH;

D O I：

10.1016/bs.pmbts.2015.04.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cornea is the tough, transparent tissue through which light first enters the eye and functions as a barrier to debris and infection as well as two-thirds of the refractive power of the eye. Corneal damage that is not promptly treated will often lead to scarring and vision impairment. Due to the limited options currently available to treat corneal scars, the identification and isolation of stem cells in the cornea has received much attention, as they may have potential for autologous, cell-based approaches to the treatment of damaged corneal tissue.

引用

页码：25 / 41

页数：17

共 114 条

[21] Tracing the Fate of Limbal Epithelial Progenitor Cells in the Murine Cornea [J].

Di Girolamo, N. ;

Bobba, S. ;

Raviraj, V. ;

Delic, N. C. ;

Slapetova, I. ;

Nicovich, P. R. ;

Halliday, G. M. ;

Wakefield, D. ;

Whan, R. ;

Lyons, J. G. .

STEM CELLS, 2015, 33 (01) :157-169

[22] Development and Characterization of a Full-Thickness Acellular Porcine Cornea Matrix for Tissue Engineering [J].

Du, Liqun ;

Wu, Xinyi .

ARTIFICIAL ORGANS, 2011, 35 (07) :691-705

[23] Multipotent stem cells in human corneal stroma [J].

Du, YD ;

Funderburgh, ML ;

SundarRaj, N ;

Funderburgh, JL .

STEM CELLS, 2005, 23 (09) :1266-1275

[24] Secretion and organization of a cornea-like tissue in vitro by stem cells from human corneal stroma [J].

Du, Yiqin ;

SundarRaj, Nirmala ;

Funderburgh, Martha L. ;

Harvey, Stephen A. ;

Birk, David E. ;

Funderburgh, James L. .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2007, 48 (11) :5038-5045

[25] Stem Cell Therapy Restores Transparency to Defective Murine Corneas [J].

Du, Yiqin ;

Carlson, Eric C. ;

Funderburgh, Martha L. ;

Birk, David E. ;

Pearlman, Eric ;

Guo, Naxin ;

Kao, Winston W. -Y. ;

Funderburgh, James L. .

STEM CELLS, 2009, 27 (07) :1635-1642

[26] CORNEAL EPITHELIAL WOUND-HEALING [J].

DUA, HS ;

GOMES, JAP ;

SINGH, A .

BRITISH JOURNAL OF OPHTHALMOLOGY, 1994, 78 (05) :401-408

[27] Localisation of Epithelial Cells Capable of Holoclone Formation In Vitro and Direct Interaction with Stromal Cells in the Native Human Limbal Crypt [J].

Dziasko, Marc A. ;

Armer, Hannah E. ;

Levis, Hannah J. ;

Shortt, Alex J. ;

Tuft, Stephen ;

Daniels, Julie T. .

PLOS ONE, 2014, 9 (04)

[28] Allogenic Limbo-keratoplasty with Conjunctivoplasty, Mitomycin C, and Amniotic Membrane for Bilateral Limbal Stem Cell Deficiency [J].

Eberwein, Philipp ;

Boehringer, Daniel ;

Schwartzkopff, Johannes ;

Birnbaum, Florian ;

Reinhard, Thomas .

OPHTHALMOLOGY, 2012, 119 (05) :930-937

[29] Adipose-Derived Stem Cells on Hyaluronic Acid-Derived Scaffold A New Horizon in Bioengineered Cornea [J].

Espandar, Ladan ;

Bunnell, Bruce ;

Wang, Guo Yong ;

Gregory, Paula ;

McBride, Christine ;

Moshirfar, Majid .

ARCHIVES OF OPHTHALMOLOGY, 2012, 130 (02) :202-208

[30] Keratocyte and fibroblast phenotypes in the repairing cornea [J].

Fini, ME .

PROGRESS IN RETINAL AND EYE RESEARCH, 1999, 18 (04) :529-551

← 1 2 3 4 5 6 7 8 9 10 →