Successful multimodality therapy of recurrent multifocal juvenile granulosa cell tumor of the ovary

被引:18
作者
Erdreich-Epstein, A
Monforte, HL
Lavey, RS
Joshi, S
Phillips, JD
Villablanca, JG
机构
[1] Childrens Hosp Los Angeles, Div Hematol Oncol, Keck Sch Med, Dept Pediat, Los Angeles, CA 90027 USA
[2] Childrens Hosp Los Angeles, Dept Pathol, Keck Sch Med, Los Angeles, CA 90027 USA
[3] Childrens Hosp Los Angeles, Dept Radiat Oncol, Keck Sch Med, Los Angeles, CA 90027 USA
[4] Univ So Calif, Los Angeles, CA USA
[5] Univ N Carolina, Dept Surg, Sch Med, Chapel Hill, NC USA
关键词
autologous bone marrow transplant; chemotherapy; juvenile granulosa cell tumor; radiation;
D O I
10.1097/00043426-200203000-00015
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Juvenile granulosa cell tumor (JGCT) of the ovary, a rare pediatric cancer, carries a very poor prognosis in advanced and recurrent cases. A 10-year-old girl with stage IA JGCT, initially treated with resection only, presented with extensive unresectable multifocal pelvic recurrence. She underwent surgery, chemotherapy (cisplatin/paclitaxel alternating with cisplatin/cyclophosphamide/etoposide/bleomycin), myeloablative chemotherapy (carboplatin/etoposide/melphalan) with autologous bone marrow transplant, and pelvic radiation. She tolerated therapy well and is in complete remission 69 months after her recurrence.
引用
收藏
页码:229 / 233
页数:5
相关论文
共 16 条
  • [1] BISCOTTI CV, 1989, ARCH PATHOL LAB MED, V113, P40
  • [2] Juvenile granulosa cell tumors of the ovary in children and adolescents: Results from 33 patients registered in a prospective cooperative study
    Calaminus, G
    Wessalowski, R
    Harms, D
    Gobel, U
    [J]. GYNECOLOGIC ONCOLOGY, 1997, 65 (03) : 447 - 452
  • [3] Bleomycin, etoposide, and cisplatin combination therapy of ovarian granulosa cell tumors and other stromal malignancies: A Gynecologic Oncology Group study
    Homesley, HD
    Bundy, BN
    Hurteau, JA
    Roth, LM
    [J]. GYNECOLOGIC ONCOLOGY, 1999, 72 (02) : 131 - 137
  • [4] Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid
    Matthay, KK
    Villablanca, JG
    Seeger, RC
    Stram, DO
    Harris, RE
    Ramsay, NK
    Swift, P
    Shimada, H
    Black, CT
    Brodeur, GM
    Gerbing, RB
    Reynolds, CP
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (16) : 1165 - 1173
  • [5] Miller BE, 1997, CANCER, V79, P1951, DOI 10.1002/(SICI)1097-0142(19970515)79:10<1951::AID-CNCR16>3.0.CO
  • [6] 2-U
  • [7] Ozols RF, 2000, SEMIN ONCOL, V27, P3
  • [8] Cisplatin (P), vinblastine (V) and bleomycin (B) combination chemotherapy in recurrent or advanced granulosa(-theca) cell tumours of the ovary. An EORTC gynaecological cancer cooperative group study
    Pecorelli, S
    Wagenaar, HC
    Vergote, IB
    Curran, D
    Beex, LVA
    Wiltshaw, E
    Vermorken, JB
    [J]. EUROPEAN JOURNAL OF CANCER, 1999, 35 (09) : 1331 - 1337
  • [9] Management of advanced juvenile granulosa cell tumor of the ovary
    Powell, JL
    Otis, CN
    [J]. GYNECOLOGIC ONCOLOGY, 1997, 64 (02) : 282 - 284
  • [10] MANAGEMENT OF ADVANCED JUVENILE GRANULOSA-CELL TUMOR OF THE OVARY
    POWELL, JL
    JOHNSON, NA
    BAILEY, CL
    OTIS, CN
    [J]. GYNECOLOGIC ONCOLOGY, 1993, 48 (01) : 119 - 123