Successful multimodality therapy of recurrent multifocal juvenile granulosa cell tumor of the ovary

被引:18
作者
Erdreich-Epstein, A
Monforte, HL
Lavey, RS
Joshi, S
Phillips, JD
Villablanca, JG
机构
[1] Childrens Hosp Los Angeles, Div Hematol Oncol, Keck Sch Med, Dept Pediat, Los Angeles, CA 90027 USA
[2] Childrens Hosp Los Angeles, Dept Pathol, Keck Sch Med, Los Angeles, CA 90027 USA
[3] Childrens Hosp Los Angeles, Dept Radiat Oncol, Keck Sch Med, Los Angeles, CA 90027 USA
[4] Univ So Calif, Los Angeles, CA USA
[5] Univ N Carolina, Dept Surg, Sch Med, Chapel Hill, NC USA
关键词
autologous bone marrow transplant; chemotherapy; juvenile granulosa cell tumor; radiation;
D O I
10.1097/00043426-200203000-00015
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Juvenile granulosa cell tumor (JGCT) of the ovary, a rare pediatric cancer, carries a very poor prognosis in advanced and recurrent cases. A 10-year-old girl with stage IA JGCT, initially treated with resection only, presented with extensive unresectable multifocal pelvic recurrence. She underwent surgery, chemotherapy (cisplatin/paclitaxel alternating with cisplatin/cyclophosphamide/etoposide/bleomycin), myeloablative chemotherapy (carboplatin/etoposide/melphalan) with autologous bone marrow transplant, and pelvic radiation. She tolerated therapy well and is in complete remission 69 months after her recurrence.
引用
收藏
页码:229 / 233
页数:5
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