Mushroom tyrosinase inhibitory activity and major fatty acid constituents of Amazonian native flora oils

被引：0

作者：

Teixeira, Raquel da Silva ^{[1
]}

Rocha, Paula Rafaela ^{[1
]}

Polonini, Hudson Caetano ^{[1
,2
]}

Fernandes Brandao, Marcos Antonio ^{[1
,2
]}

Afonso Miranda Chaves, Maria das Gracas ^{[2
]}

Barbosa Raposo, Nadia Rezende ^{[1
,2
]}

机构：

[1] Univ Fed Juiz de Fora, NIQUA, BR-36036900 Juiz De Fora, MG, Brazil

[2] Univ Fed Juiz de Fora, NUPICS, BR-36036900 Juiz De Fora, MG, Brazil

来源：

BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2012年 / 48卷 / 03期

关键词：

Amazonian plants/evaluation/dermatological use; Skin lightening agents; Tyrosinase/inhibition/in vitro evaluation; Melanin; Hyperpigmentation/treatment; IN-VITRO; EXTRACTS; PLANTS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In order to treat hyperpigmentation-related problems, there has been a global trend in developing cosmetics claiming to have skin-whitening properties, which act by inhibiting melanin biosynthesis. The objective of this work was to evaluate the in vitro mushroom tyrosinase inhibitory activity of five Amazonian native flora oils, and solo verify the possibility of their incorporation into cosmetic products. In addition, the fatty acid composition of the essential oils was determined by gas chromatography-flame ionisation detection in order to determine the main components of these oils. The tyrosinase inhibitory activity of the tested oils was found to be in the following order: acai (IA(50) = 66.08 mu g mL(-1)) > tucuma > pataua > pracaxi > castanha do Brasil. This study suggests that acai oil has great potential in the treatment of hyperpigmentation and other related disorders, due to its considerable tyrosinase inhibitory activity.

引用

页码：399 / 404

页数：6

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