AID for innate immunity to retroviral transformation

被引:3
作者
Schlissel, MS [1 ]
Kuo, TC [1 ]
机构
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Div Immunol, Berkeley, CA 94720 USA
关键词
D O I
10.1016/j.immuni.2006.06.005
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
AID is a cytidine deaminase essential for class switch recombination and somatic hypermutation during the humoral immune response. In this issue of Immunity, Gourzi et al. (2006) show that AID also plays a critical role in innate immunity to virally induced acute pro-B cell leukemia.
引用
收藏
页码:671 / 672
页数:2
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