Effects of prolactin on DNA synthesis, cholesterol stores, and steroidogenesis in the adrenal cortex of dexamethasone-treated guinea pigs

被引：0

作者：

Sautin, YY ^{[1
]}

Kovzun, EI ^{[1
]}

Tronko, ND ^{[1
]}

Mikosha, AS ^{[1
]}

机构：

[1] UKRAINE ACAD MED SCI,VP KOMISSARENKO INST ENDOCRINOL & METAB,UA-252655 KIEV,UKRAINE

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1997年 / 123卷 / 01期

关键词：

prolactin; adrenal cortex; dexamethasone; steroidogenesis; cholesterol;

D O I：

10.1007/BF02764366

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The effect of prolactin on the guinea pig adrenal cortex is studied in a model of dexamethasone-induced atrophy. Prolactin elevates the content of free and total cholesterol per tissue weight but does not affect the specific activity of hydrocortisone synthesized in the presence of labeled cholesterol. It is concluded that prolactin has no direct effect on hormonopoiesis but activates proliferative processes in the adrenal cortex.

引用

页码：14 / 16

页数：3

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