Study of cobalt ferrite nanosuspensions for low-frequency ferromagnetic hyperthermia

被引：68

作者：

Kashevsky, Bronislav E. ^{[1
]}

Agabekov, Vladimir E. ^{[2
]}

Kashevsky, Sergei B. ^{[1
]}

Kekalo, Katsiaryna A. ^{[2
]}

Manina, Elena Yu. ^{[3
]}

Prokhorov, Igor V. ^{[1
]}

Ulashchik, Vladimir S. ^{[3
]}

机构：

[1] Belarus Acad Sci, AV Luikov Heat & Mass Transfer Inst, Minsk 220072, BELARUS

[2] Belarus Acad Sci, Inst Chem New Mat, Minsk 220141, BELARUS

[3] Belarus Acad Sci, Inst Physiol, Minsk 220072, BELARUS

来源：

PARTICUOLOGY | 2008年 / 6卷 / 05期

关键词：

Cobalt ferrite nanoparticles; Magnetic suspensions; Dynamic magnetic hysteresis; Medical hyperthermia;

D O I：

10.1016/j.partic.2008.07.001

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

High-coercive cobalt ferrite nanoparticles were synthesized and studied for magnetic hyperthermia by direct injection of their suspension into a tumor and application of a strong audio-frequency magnetic field for heating. Physical (dynamic magnetic hysteresis and heat generation in both liquid and solid dispersions), biological (toxicity and penetration of particles in therapeutic quantities into mouse tumor tissue) as well as other properties of the particles were studied. A model was developed to describe the magnetodynamics in suspensions of magnetic nanoclusters with an account for both Brownian and regular rotations, to provide understanding of observed phenomena. The experimental and theoretical techniques developed have formed a basis for controllable synthesis of the magnetic nanoparticles for low-frequency heat generation in medical and other applications. (C) 2008 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：322 / 333

页数：12

共 26 条

[11] Audio-frequency heating of particulate magnetic systems [J].

Kashevsky, B. E. ;

Prokhorov, I. V. ;

Kashevsky, S. B. .

CHINA PARTICUOLOGY, 2007, 5 (1-2) :84-92

[12]

KASHEVSKY BE, 2006, 12 PLEOS C MAGN FLUI, P317

[13] In vivo investigation of cobalt ferrite-based magnetic fluid and magnetoliposomes using morphological tests [J].

Kückelhaus, S ;

Reis, SC ;

Carneiro, MF ;

Tedesco, AC ;

Oliveira, DM ;

Lima, ECD ;

Morais, PC ;

Azevedo, RB ;

Lacava, ZGM .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2004, 272 :2402-2403

[14]

Lifshitz E. M., 1981, PHYS KINETICS

[15]

Mee CD., 1964, PHYS MAGNETIC RECORD

[16] Synthesis and assembly of high-quality cobalt ferrite nanocrystals prepared by a modified sol-gel technique [J].

Meron, T ;

Rosenberg, Y ;

Lereah, Y ;

Markovich, G .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2005, 292 :11-16

[17]

*NAT BUR STAND US, 1967, NAT BUR STAND US MON, V25

[18]

*NAT BUR STAND US, 1971, NAT BUR STAND US MON, V25

[19]

NEEL L, 1947, CR HEBD ACAD SCI, V224, P1550

[20]

Odenbach S., 2002, Magnetoviscous Effects in Ferrofluids

← 1 2 3 →