Study of cobalt ferrite nanosuspensions for low-frequency ferromagnetic hyperthermia

被引：68

作者：

Kashevsky, Bronislav E. ^{[1
]}

Agabekov, Vladimir E. ^{[2
]}

Kashevsky, Sergei B. ^{[1
]}

Kekalo, Katsiaryna A. ^{[2
]}

Manina, Elena Yu. ^{[3
]}

Prokhorov, Igor V. ^{[1
]}

Ulashchik, Vladimir S. ^{[3
]}

机构：

[1] Belarus Acad Sci, AV Luikov Heat & Mass Transfer Inst, Minsk 220072, BELARUS

[2] Belarus Acad Sci, Inst Chem New Mat, Minsk 220141, BELARUS

[3] Belarus Acad Sci, Inst Physiol, Minsk 220072, BELARUS

来源：

PARTICUOLOGY | 2008年 / 6卷 / 05期

关键词：

Cobalt ferrite nanoparticles; Magnetic suspensions; Dynamic magnetic hysteresis; Medical hyperthermia;

D O I：

10.1016/j.partic.2008.07.001

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

High-coercive cobalt ferrite nanoparticles were synthesized and studied for magnetic hyperthermia by direct injection of their suspension into a tumor and application of a strong audio-frequency magnetic field for heating. Physical (dynamic magnetic hysteresis and heat generation in both liquid and solid dispersions), biological (toxicity and penetration of particles in therapeutic quantities into mouse tumor tissue) as well as other properties of the particles were studied. A model was developed to describe the magnetodynamics in suspensions of magnetic nanoclusters with an account for both Brownian and regular rotations, to provide understanding of observed phenomena. The experimental and theoretical techniques developed have formed a basis for controllable synthesis of the magnetic nanoparticles for low-frequency heat generation in medical and other applications. (C) 2008 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：322 / 333

页数：12

共 26 条

[1] Magnetic properties and morphology of block copolymer templated ferrimagnetic CoFe2O4 nanoparticles [J].

Ahmed, SR ;

Ogale, SB ;

Kofinas, P .

IEEE TRANSACTIONS ON MAGNETICS, 2003, 39 (05) :2198-2200

[2]

BIBIK YY, 1979, ZH PRIKL KHIM, V52, P1631

[3] THERMAL FLUCTUATIONS OF A SINGLE-DOMAIN PARTICLE [J].

BROWN, WF .

PHYSICAL REVIEW, 1963, 130 (05) :1677-+

[4]

CLAESSON EM, 2007, J PHYS CONDENS MATT, V19, P46

[5]

Döker O, 2003, REV ADV MATER SCI, V5, P498

[6] Ferromagnetic colloid for studying magnetic structures [J].

Elmore, WC .

PHYSICAL REVIEW, 1938, 54 (04) :309-310

[7] SUPERPARAMAGNETISM AND RELAXATION EFFECTS IN GRANULAR NI-SIO2 AND NI-AL2O3 FILMS [J].

GITTLEMA.JI ;

ABELES, B ;

BOZOWSKI, S .

PHYSICAL REVIEW B, 1974, 9 (09) :3891-3897

[8]

HIMOIIZAKA J, 1978, Patent No. 4094804

[9] Synthesis of highly crystalline and monodisperse cobalt ferrite nanocrystals [J].

Hyeon, T ;

Chung, Y ;

Park, J ;

Lee, SS ;

Kim, YW ;

Park, BH .

JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (27) :6831-6833

[10] Study of energy dissipation in a suspension of particles with magnetic hysteresis in alternating supercritical-frequency field [J].

Kashevskii, BE ;

Kashevskii, SB ;

Prokhorov, IV ;

Ivanov, VE .

COLLOID JOURNAL, 2006, 68 (01) :54-58

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