An expeditious stereoselective synthesis of natural (-)-Cassine via cascade HWE [3+2]-cycloaddition process

被引：23

作者：

Herdeis, C ^{[1
]}

Küpper, P ^{[1
]}

Plé, S ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Pharm & Lebensmittelchem, D-97074 Wurzburg, Germany

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 03期

关键词：

D O I：

10.1039/b516888k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

L-Rhamnose is transformed to (-)-Cassine via a remarkable four step one pot reaction. The Horner-Wadsworth-Emmons [3 + 2]-1,3-dipolar cycloaddition reaction cascade is the pivotal step in this reaction sequence and makes the synthesis highly efficient.

引用

页码：524 / 529

页数：6

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