Deregulated Akt/mTOR signaling interferes with the balance between keratinocyte proliferation and differentiation and thereby contributes to the pathogenesis of psoriasis

被引：0
|
作者：
Franke, O. [1 ]
Eiser, A. [1 ]
Malisiewicz, B. [1 ]
Diehl, S. [1 ]
Lang, V. [1 ]
Steinhorst, K. [1 ]
Boehncke, W. [2 ]
Buerger, C. [1 ]
机构：
[1] Goethe Univ Frankfurt, Dept Dermatol, D-60590 Frankfurt, Germany
[2] Hpital Univ Genve, Serv Dermatol, CH-1211 Geneva, Switzerland
来源：
EXPERIMENTAL DERMATOLOGY | 2013年 / 22卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：E9 / E9
页数：1
相关论文
共 32 条
  • [1] Interleukin-1β interferes with the balance between proliferation and differentiation through insulin resistance in human keratinocytes Vimplications for psoriasis pathogenesis
    Buerger, C.
    Richter, B.
    Malisiewicz, B.
    Hardt, K.
    Diehl, S.
    Boehncke, W.
    EXPERIMENTAL DERMATOLOGY, 2011, 20 (02) : 206 - 206
  • [2] Interleukin-1β interferes with the balance between proliferation and differentiation through insulin resistance in human keratinocytes - implications for psoriasis pathogenesis
    Buerger, Claudia
    Richter, Beatrice
    Woth, Kathrin
    Malisiewicz, Bartosz
    Diehl, Sandra
    Hardt, Katja
    Boehncke, Wolf-Henning
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 : S75 - S75
  • [3] Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation
    Buerger, Claudia
    Shirsath, Nitesh
    Lang, Victoria
    Berard, Alina
    Diehl, Sandra
    Kaufmann, Roland
    Boehncke, Wolf-Henning
    Wolf, Peter
    PLOS ONE, 2017, 12 (07):
  • [4] Cytokine mediated induction of mTOR signalling prevents proper differentiation of keratinocytes and contributes to the pathogenesis of psoriasis
    Buerger, C.
    Hofmann, M.
    Lang, V.
    Diehl, S.
    Malisiewicz, B.
    Fotiou, K.
    Boehncke, W.
    Kaufmann, R.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 : S45 - S45
  • [5] Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling
    Altomare, D. A.
    Khaled, A. R.
    CURRENT MEDICINAL CHEMISTRY, 2012, 19 (22) : 3748 - 3762
  • [6] USP18 contributes to the proliferation and migration of ovarian cancer cells by regulating the AKT/mTOR signaling pathway
    Liu, Meiqin
    Gao, Shile
    Xu, Xingjun
    Zhang, Lijie
    Xu, Bin
    Lu, Donghui
    ACTA BIOCHIMICA POLONICA, 2022, 69 (02) : 417 - 422
  • [7] Crosstalk between Activin A and Shh signaling contributes to the proliferation and differentiation of antler chondrocytes
    Ma, Li
    Duan, Cui-Cui
    Yang, Zhan-Qing
    Ding, Jun-Li
    Liu, Shu
    Yue, Zhan-Peng
    Guo, Bin
    BONE, 2019, 123 : 176 - 188
  • [8] Cytokine mediated induction of mTORC1 signaling prevents proper differentiation of keratinocytes and contributes to the pathogenesis of psoriasis
    Lang, V.
    Eiser, A.
    Malisiewicz, B.
    Diehl, S.
    Steinhorst, K.
    Boehncke, W.
    Buerger, C.
    EXPERIMENTAL DERMATOLOGY, 2014, 23 (03) : E10 - E10
  • [9] Cytokine mediated induction of mTORC1 signaling prevents proper differentiation of keratinocytes and contributes to the pathogenesis of psoriasis
    Lang, V.
    Diehl, S.
    Kaufmann, R.
    Boehncke, W.
    Buerger, C.
    EXPERIMENTAL DERMATOLOGY, 2015, 24 (03) : E6 - E6
  • [10] The interaction between STAT3 and nAChRα1 interferes with nicotine-induced atherosclerosis via Akt/mTOR signaling cascade
    Xu, Shuang
    Ni, Huaner
    Chen, Hangwei
    Dai, Qiuyan
    AGING-US, 2019, 11 (19): : 8120 - 8138
1234