Movement disorders in multiple sclerosis: causal or coincidental association?

被引:35
作者
Nociti, V. [1 ,3 ]
Bentivoglio, A. R. [1 ]
Frisullo, G. [1 ]
Fasano, A. [1 ]
Soleti, F. [1 ]
Iorio, R. [1 ]
Loria, G. [1 ]
Patanella, A. K. [1 ]
Marti, A. [1 ]
Tartaglione, T. [2 ]
Tonali, P. A. [1 ,3 ]
Batocchi, A. P. [1 ,3 ]
机构
[1] Univ Cattolica Sacro Cuore, Inst Neurol, Dept Neurosci, I-00167 Rome, Italy
[2] Univ Cattolica Sacro Cuore, Inst Radiol, Dept Bioimaging & Radiol Sci, I-00167 Rome, Italy
[3] Fdn Don C Gnocchi, Dept Neurorehabil, Rome, Italy
关键词
blepharospasm; hemidystonia; hemifacial spasm; movement disorders; multiple sclerosis; parkinsonism; tourettism;
D O I
10.1177/1352458508094883
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Despite the relatively frequent involvement of the basal ganglia and subthalamic nucleus by multiple sclerosis (MS) plaques, movement disorders (MD), other than tremor secondary to cerebellar or brain-stem lesions, are uncommon clinical manifestations of MS. MD were present in 12 of 733 patients with MS (1.6%): three patients had parkinsonism, two blepharospasm, five hemifacial spasm, one hemidystonia, and one tourettism. MD in patients with MS are often secondary to demyelinating disease. Also in cases without response to steroid treatment and demyelinating lesions in critical regions, it is not possible to exclude that MD and MS are causally related. Multiple Sclerosis 2008; 14: 1284-1287. http://msj.sagepub.com
引用
收藏
页码:1284 / 1287
页数:4
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