Urinary Incontinence Before and After Bariatric Surgery

被引:68
作者
Subak, Leslee L. [1 ,2 ,3 ,4 ]
King, Wendy C. [5 ]
Belle, Steven H. [5 ,6 ]
Chen, Jia-Yuh [6 ]
Courcoulas, Anita P. [7 ]
Ebel, Faith E. [8 ]
Flum, David R. [9 ]
Khandelwal, Saurabh [9 ]
Pender, John R. [10 ]
Pierson, Sheila K. [7 ]
Pories, Walter J. [10 ]
Steffen, Kristine J. [11 ]
Strain, Gladys W. [8 ]
Wolfe, Bruce M.
Huang, Alison J.
机构
[1] Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Urol, San Francisco, CA 94143 USA
[4] San Francisco VA Med Ctr, San Francisco, CA USA
[5] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA
[6] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Biostat, Pittsburgh, PA 15261 USA
[7] Univ Pittsburgh, Med Ctr, Dept Surg, Pittsburgh, PA USA
[8] Weill Cornell Med Coll, GI Metab & Bariatr Surg, New York, NY USA
[9] Univ Washington, Dept Surg, Seattle, WA 98195 USA
[10] E Carolina Univ, Brody Sch Med, Dept Surg, Greenville, NC USA
[11] Univ N Dakota, Sch Med & Hlth Sci, Neuropsychiat Res Unit, Dept Neurosci, Grand Forks, ND 58201 USA
关键词
PELVIC FLOOR DISORDERS; QUALITY-OF-LIFE; WEIGHT-LOSS; FECAL INCONTINENCE; PHYSICAL-ACTIVITY; UNITED-STATES; RISK-FACTORS; OBESE WOMEN; PREVALENCE; OVERWEIGHT;
D O I
10.1001/jamainternmed.2015.2609
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
IMPORTANCE Among women and men with severe obesity, evidence for improvement in urinary incontinence beyond the first year after bariatric surgery-induced weight loss is lacking. OBJECTIVES To examine change in urinary incontinence before and after bariatric surgery and to identify factors associated with improvement and remission among women and men in the first 3 years after bariatric surgery. DESIGN, SETTING, AND PARTICIPANTS The Longitudinal Assessment of Bariatric Surgery 2 is an observational cohort study at 10 US hospitals in 6 geographically diverse clinical centers. Participants were recruited between February 21, 2005, and February 17, 2009. Adults undergoing first-time bariatric surgical procedures as part of clinical care by participating surgeons between March 14, 2006, and April 24, 2009, were followed up for 3 years (through October 24, 2012). INTERVENTION Participants undergoing bariatric surgery completed research assessments before the procedure and annually thereafter. MAIN OUTCOMES AND MEASURES The frequency and type of urinary incontinence episodes in the past 3 months were assessed using a validated questionnaire. Prevalent urinary incontinence was defined as at least weekly urinary incontinence episodes, and remission was defined as change from prevalent urinary incontinence at baseline to less than weekly urinary incontinence episodes at follow-up. RESULTS Of 2458 participants, 1987 (80.8%) completed baseline and follow-up assessments. At baseline, the median age was 47 years (age range, 18-78 years), the median body mass index was 46 kg/m(2) (range, 34-94 kg/m(2)), and 1565 of 1987 (78.8%) were women. Urinary incontinence was more prevalent among women (49.3%; 95% CI, 46.9%-51.9%) than men (21.8%; 95% CI, 18.2%-26.1%) (P <.001). After a mean 1-year weight loss of 29.5%(95% CI, 29.0%-30.1%) in women and 27.0%(95% CI, 25.9%-28.6%) in men, year 1 urinary incontinence prevalence was significantly lower among women (18.3%; 95% CI, 16.4%-20.4%) and men (9.8%; 95% CI, 7.2%-13.4%) (P <.001 for all). The 3-year prevalence was higher than the 1-year prevalence for both sexes (24.8%; 95% CI, 21.8%-26.5% among women and 12.2%; 95% CI, 9.0%-16.4% among men) but was substantially lower than baseline (P <.001 for all). Weight loss was independently related to urinary incontinence remission (relative risk, 1.08; 95% CI, 1.06-1.10 in women and 1.07; 95% CI, 1.02-1.13 in men) per 5% weight loss, as were younger age and the absence of a severe walking limitation. CONCLUSIONS AND RELEVANCE Among women and men with severe obesity, bariatric surgery was associated with substantially reduced urinary incontinence over 3 years. Improvement in urinary incontinence may be an important benefit of bariatric surgery.
引用
收藏
页码:1378 / 1387
页数:10
相关论文
共 43 条
  • [1] Baseline characteristics of participants in the Longitudinal Assessment of Bariatric Surgery-2 (LABS-2) study
    Belle, Steven H.
    Berk, Paul D.
    Chapman, William H.
    Christian, Nicholas J.
    Courcoulas, Anita P.
    Dakin, Greg F.
    Flum, David R.
    Horlick, Mary
    King, Wendy C.
    McCloskey, Carol A.
    Mitchell, James E.
    Patterson, Emma J.
    Pender, John R.
    Steffen, Kristine J.
    Thirlby, Richard C.
    Wolfe, Bruce M.
    Yanovski, Susan Z.
    [J]. SURGERY FOR OBESITY AND RELATED DISEASES, 2013, 9 (06) : 926 - 935
  • [2] Urinary incontinence self-report questions: reproducibility and agreement with bladder diary
    Bradley, Catherine S.
    Brown, Jeanette S.
    Van Den Eeden, Stephen K.
    Schembri, Michael
    Ragins, Arona
    Thom, David H.
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2011, 22 (12) : 1565 - 1571
  • [3] Intensive Lifestyle Intervention Reduces Urinary Incontinence in Overweight/Obese Men with Type 2 Diabetes: Results from the Look AHEAD Trial
    Breyer, Benjamin N.
    Phelan, Suzanne
    Hogan, Patricia E.
    Rosen, Raymond C.
    Kitabchi, Abbas E.
    Wing, Rena R.
    Brown, Jeanette S.
    [J]. JOURNAL OF UROLOGY, 2014, 192 (01) : 144 - 149
  • [4] Urinary incontinence in older women: Who is at risk?
    Brown, JS
    Seeley, DG
    Fong, J
    Black, DM
    Ensrud, KE
    Grady, D
    [J]. OBSTETRICS AND GYNECOLOGY, 1996, 87 (05) : 715 - 721
  • [5] Buckley BS, 2010, UROLOGY, V76, P265, DOI 10.1016/j.urology.2009.11.078
  • [6] Changes in urinary and fecal incontinence symptoms with weight loss surgery in morbidity obese women
    Burgio, Kathryn L.
    Richter, Holly E.
    Clements, Ronald H.
    Redden, David T.
    Goode, Patricia S.
    [J]. OBSTETRICS AND GYNECOLOGY, 2007, 110 (05) : 1034 - 1040
  • [7] TREATMENT SEEKING FOR URINARY-INCONTINENCE IN OLDER ADULTS
    BURGIO, KL
    IVES, DG
    LOCHER, JL
    ARENA, VC
    KULLER, LH
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1994, 42 (02) : 208 - 212
  • [8] Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity
    Courcoulas, Anita P.
    Christian, Nicholas J.
    Belle, Steven H.
    Berk, Paul D.
    Flum, David R.
    Garcia, Luis
    Horlick, Mary
    Kalarchian, Melissa A.
    King, Wendy C.
    Mitchell, James E.
    Patterson, Emma J.
    Pender, John R.
    Pomp, Alfons
    Pories, Walter J.
    Thirlby, Richard C.
    Yanovski, Susan Z.
    Wolfe, Bruce M.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 310 (22): : 2416 - 2425
  • [9] Economic Burden of Urgency Urinary Incontinence in the United States: A Systematic Review
    Coyne, Karin S.
    Wein, Alan
    Nicholson, Sean
    Kvasz, Marion
    Chen, Chieh-I
    Milsom, Ian
    [J]. JOURNAL OF MANAGED CARE PHARMACY, 2014, 20 (02): : 130 - 140
  • [10] Clinical and instrumental evaluation of pelvic floor disorders before and after bariatric surgery in obese women
    Cuicchi, Dajana
    Lombardi, Raffaele
    Cariani, Stefano
    Leuratti, Luca
    Lecce, Ferdinando
    Cola, Bruno
    [J]. SURGERY FOR OBESITY AND RELATED DISEASES, 2013, 9 (01) : 69 - 76