HLA-B27 and HLA-B73 polymorphism and its role on antigenicity, peptide presentation, and disease susceptibility

被引：6
|
作者：
DeCastro, JAL
机构：
来源：
CLINICAL RHEUMATOLOGY | 1996年 / 15卷
关键词：
HLA-B27; HLA-B73; spondyloarthropathies; antigen presentation; T-cell recognition;
D O I：
10.1007/BF03342650
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Current ideas on the structure, evolution, and disease association of HLA-B27 antigens are presented, with emphasis on the effect of HLA-B27 polymorphism on T-cell recognition and antigen-presenting properties of these molecules. The molecular relationship between HLA-B27 and HLA-B73, and its implications for a putative pathogenetic role of the later antigen are discussed.
引用
收藏
页码：67 / 71
页数：5
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