Marine Low Molecular Weight Natural Products as Potential Cancer Preventive Compounds

被引：38

作者：

Stonik, Valentin A. ^{[1
,2
]}

Fedorov, Sergey N. ^{[1
]}

机构：

[1] Russian Acad Sci, GB Elyakov Pacific Inst Bioorgan Chem, Far Eastern Branch, Vladivostok 690950, Russia

[2] Far East Fed Univ, Sch Nat Sci, Vladivostok 690950, Russia

来源：

MARINE DRUGS | 2014年 / 12卷 / 02期

关键词：

marine organisms; secondary metabolites; cancer preventive; chemopreventive; anticarcinogenic; mechanisms of action; EUPENTACTA FRAUDATRIX. STRUCTURE; MINOR NONSULFATED TETRAOSIDES; TRITERPENE GLYCOSIDES; SARCOPHYTOL-A; BIOLOGICAL ACTION; UBC13-UEV1A INTERACTION; HISTONE DEACETYLASE; CELL-PROLIFERATION; ANTITUMOR-ACTIVITY; TUMOR PROMOTION;

D O I：

10.3390/md12020636

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Due to taxonomic positions and special living environments, marine organisms produce secondary metabolites that possess unique structures and biological activities. This review is devoted to recently isolated and/or earlier described marine compounds with potential or established cancer preventive activities, their biological sources, molecular mechanisms of their action, and their associations with human health and nutrition. The review covers literature published in 2003-2013 years and focuses on findings of the last 2 years.

引用

页码：636 / 671

页数：36

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