Host, Gender, and Early-Life Factors as Risks for Chronic Obstructive Pulmonary Disease

被引:6
作者
Han, MeiLan K. [1 ]
Martinez, Fernando J. [2 ]
机构
[1] Univ Michigan, Sch Med, Div Pulm & Crit Care Med, 3916 Taubman Ctr,1500 East Med Ctr Dr, Ann Arbor, MI 48109 USA
[2] Weill Cornell Med, Div Pulm & Crit Care Med, Internal Med, New York, NY USA
关键词
COPD; Gender; Genetics; Tobacco; Exposures; OUTDOOR AIR-POLLUTION; ADULT LUNG-FUNCTION; DEVELOPING-COUNTRIES; TOBACCO-SMOKE; COPD; HEALTH; SEX; EMPHYSEMA; EXPOSURE; WOMEN;
D O I
10.1016/j.ccm.2020.06.009
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Although smoking results in lung pathology in many, still not all smokers develop chronic obstructive pulmonary disease (COPD). Roughly a quarter of patients with COPD have never smoked. An understanding of both host and environmental factors beyond smoking that contribute to disease development remain critical to understanding disease prevention and ultimately effectively intervene. In this article, we summarize host factors, including genetics and gender, as well as early-life events that contribute to the development of COPD. © 2020
引用
收藏
页码:329 / 337
页数:9
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