Update on fertility preservation for younger women with breast cancer

被引：10

作者：

Warner, Ellen ^{[1
,4
]}

Glass, Karen ^{[2
,3
,4
]}

Foong, Shu ^{[5
,6
]}

Sandwith, Emily ^{[6
]}

机构：

[1] Sunnybrook Odette Canc Ctr, Div Med Oncol, Toronto, ON, Canada

[2] Sunnybrook Odette Canc Ctr, Div Obstet Gynecol, Toronto, ON, Canada

[3] CReATe Fertil Ctr, Toronto, ON, Canada

[4] Univ Toronto, Toronto, ON, Canada

[5] Reg Fertil Program, Calgary, AB, Canada

[6] Univ Calgary, Calgary, AB, Canada

来源：

CANADIAN MEDICAL ASSOCIATION JOURNAL | 2020年 / 192卷 / 35期

基金：

加拿大健康研究院;

关键词：

AMERICAN-SOCIETY; PREGNANCY; SAFETY; CHEMOTHERAPY; STIMULATION; TAMOXIFEN; OUTCOMES; IMPACT;

D O I：

10.1503/cmaj.200245

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Most patients with breast cancer diagnosed during their reproductive years will require gonadotoxic adjuvant systemic chemotherapy. Explanation of the detrimental effect of chemotherapy on ovarian function in general and on fertility in particular should be part of the chemotherapy informed-consent process. Routinely discussing childbearing plans with young patients with breast cancer as soon as possible after their diagnosis and offering prompt referral to a fertility clinic to those who have not yet completed their families enables these women to choose from a number of safe and increasingly successful fertility-preservation options without delaying their cancer treatment. Moreover, merely having such a discussion sends these young women the powerfully positive message that they are expected to not only have a normal lifespan but also to continue to pursue the goals and dreams they had before their illness. © 2020 Joule Inc. or its licensors

引用

页码：E1003 / E1009

页数：7

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