Infectious Dose of Listeria monocytogenes in Outbreak Linked to Ice Cream, United States, 2015

被引:101
作者
Pouillot, Regis [1 ]
Klontz, Karl C. [1 ]
Chen, Yi [1 ]
Burall, Laurel S. [2 ]
Macarisin, Dumitru [1 ]
Doyle, Matthew [1 ]
Bally, Karen M. [3 ]
Strain, Errol [1 ]
Datta, Atin R. [2 ]
Hammack, Thomas S. [1 ]
Van Doren, Jane M. [1 ]
机构
[1] US FDA, 5001 Campus Dr, College Pk, MD 20740 USA
[2] US FDA, Laurel, MD USA
[3] Via Christi Hosp, Wichita, KS USA
关键词
CUT CANTALOUPE; GROWTH; CHEESE; RISK;
D O I
10.3201/eid2212.160165
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The relationship between the number of ingested Listeria monocytogenes cells in food and the likelihood of developing listeriosis is not well understood. Data from an outbreak of listeriosis linked to milkshakes made from ice cream produced in 1 factory showed that contaminated products were distributed widely to the public without any reported cases, except for 4 cases of severe illness in persons who were highly susceptible. The ingestion of high doses of L. monocytogenes by these patients infected through milkshakes was unlikely if possible additional contamination associated with the preparation of the milkshake is ruled out. This outbreak illustrated that the vast majority of the population did not become ill after ingesting a low level of L. monocytogenes but raises the question of listeriosis cases in highly susceptible persons after distribution of low-level contaminated products that did not support the growth of this pathogen.
引用
收藏
页码:2113 / 2119
页数:7
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