Novel electrochemical DNA biosensor based on edge-plane pyrolytic graphite for DNA interaction studies

被引：0

作者：

Augustin, Michal ^{[1
]}

Vyskocil, Vlastimil ^{[1
]}

机构：

[1] Charles Univ Prague, Fac Sci, Dept Analyt Chem, UNESCO Lab Environm Electrochem, Hlavova 8, Prague 12843 2, Czech Republic

来源：

PROCEEDINGS OF THE 15TH INTERNATIONAL STUDENTS CONFERENCE MODERN ANALYTICAL CHEMISTRY | 2019年

关键词：

biosensor; DNA; graphite; voltammetry; VOLTAMMETRIC DETERMINATION;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Carbon electrodes represent the most popular working electrodes used in electrochemical analysis of nucleic acids. Since the end of the 20th century, they have been frequently used for a lot of various applications in the field of electrochemical analysis of DNA, RNA, as well as synthetic mimics of nucleic acids such as PNA. Some of their remarkable properties enhanced their utilization as electrochemical transducers of sensors for DNA hybridization, DNA-drug interactions, or even monitoring DNA damage. The aim of the proposed study is the preparation, development, and subsequent testing of new electrochemical DNA biosensors based on relatively new type of carbon material "edge-plane" pyrolytic graphite (EPPG) and its subsequent utilization as a useful analytical tool.

引用

页码：263 / 268

页数：6

共 9 条

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