Clinical Case of Tofacitinib Therapy in Autoimmune Alopecia in Patient with Ulcerative Colitis

被引：1

作者：

Bodryagina, Evgenia ^{[1
]}

Odintsova, Alfiya ^{[2
]}

Cheremina, Natalia ^{[2
]}

Blatt, Nataliya ^{[3
]}

Akberova, Dilyara ^{[1
]}

Abdulganieva, Diana ^{[1
,2
]}

机构：

[1] Kazan State Med Univ, Kazan, Russia

[2] Republ Clin Hosp, Kazan, Russia

[3] Kazan Fed Univ, Inst Fundamental Med & Biol, Kazan, Russia

来源：

BIONANOSCIENCE | 2022年 / 12卷 / 04期

关键词：

Ulcerative colitis; Alopecia; Autoimmune disease; Tofacitinib; Inflammatory bowel disease;

D O I：

10.1007/s12668-022-01027-4

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

This article presents the clinical case of a patient with a long history of ulcerative colitis. Seven years after the onset of the disease, other autoimmune disorders such as sacroiliitis and alopecia have manifested. Ulcerative colitis is characterized by severe exacerbations, development of steroid resistance, ineffectiveness of mesalazine therapy, and onset of leukopenia when taking azathioprine and 6-mercaptopurine. Janus kinase inhibitor (tofacitinib) administration leads to remission of the disease, reduced activity of ulcerative colitis and sacroiliitis, and a resumption of hair growth was also observed.

引用

收藏

页码：1394 / 1396

页数：3

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