Severe perirenal hematoma in a patient with a single kidney treated with sunitinib for metastatic pancreatic neuroendocrine tumor

被引:2
|
作者
Zugazagoitia, Jon [1 ]
Sastre, Javier [1 ]
Barrera, Jeronimo [2 ]
Garcia, Beatriz [1 ]
Diaz-Rubio, Eduardo [1 ]
机构
[1] Hosp Clin San Carlos, Dept Med Oncol, Madrid 28040, Spain
[2] Hosp Clin San Carlos, Dept Radiol, Madrid 28040, Spain
关键词
Angiogenesis; pancreatic neuroendocrine tumor; perirenal hematoma; sunitinib; vascular homeostasis; ANGIOGENESIS;
D O I
10.4103/0973-1482.98997
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A better understanding of the angiogenic process has markedly expanded the use of antiangiogenic therapy in many solid tumors. It is known that there is a close relationship between cancer disease, vascular homeostasis, angiogenesis and coagulation cascade. In this setting, antiangiogenic therapy could interfere and potentially increase the risk of bleeding or thromboembolic events. Sunitinib is an orally available smallmolecule multikinase inhibitor recently approved for the treatment of unresectable or metastatic, well-differenciated pancreatic neuroendocrine tumors with disease progression in adults. Here we present the first case of a severe perirenal hematoma in a patient treated with sunitinib for metastatic pancreatic neuroendocrine tumor.
引用
收藏
页码:303 / 305
页数:3
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