Can we predict a favourable response to Ketogenic Diet Therapies for drug-resistant epilepsy?

被引：31

作者：

Schoeler, Natasha E. ^{[1
]}

Cross, J. Helen ^{[2
]}

Sander, Josemir W. ^{[1
]}

Sisodiya, Sanjay M. ^{[1
]}

机构：

[1] UCL, Dept Clin & Expt Epilepsy, Inst Neurol, London WC1E 6BT, England

[2] UCL, Inst Child Hlth, Great Ormond St Hosp Children, London WC1E 6BT, England

来源：

EPILEPSY RESEARCH | 2013年 / 106卷 / 1-2期

关键词：

Dietary treatments; Outcomes; Review; MODIFIED ATKINS DIET; GLYCEMIC-INDEX TREATMENT; INTRACTABLE CHILDHOOD EPILEPSY; FATTY-ACID OXIDATION; TERM-FOLLOW-UP; REFRACTORY EPILEPSY; DRAVET-SYNDROME; BETA-HYDROXYBUTYRATE; CALORIE RESTRICTION; PEDIATRIC EPILEPSY;

D O I：

10.1016/j.eplepsyres.2013.06.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ketogenic Dietary Therapies (KDT) are an effective treatment option for some people with drug-resistant epilepsy. They are, however, resource-intensive and can cause adverse side effects. Predictors of response would improve the selection process and perhaps further our understanding of the mechanisms behind dietary treatments for epilepsy. We conducted a literature review to identify factors that may influence response to KDT. We found no strong evidence that there are any specific factors that affect response. Gender and intellectual status do not seem to affect response; evidence is inconsistent for all other factors. Experimental studies may point us in the right direction for future work. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：1 / 16

页数：16

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