Primary Breast Amyloidosis Presenting Solely as Nonpalpable Microcalcifications: A Case Report With Review of the Literature

被引:9
作者
Ngendahayo, Placide [1 ]
Faverly, Daniel [2 ]
Herin, Michel [1 ]
机构
[1] IPG, B-6041 Gosselies, Belgium
[2] Lab CMP, Brussels, Belgium
关键词
breast; primary amyloidosis; microcalcification; LOCALIZED AMYLOIDOSIS; OSSEOUS METAPLASIA; TUMOR; LYMPHOMA; MASSES; DEPOSITION; CARCINOMA;
D O I
10.1177/1066896912457203
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Primary breast amyloidosis is a rare disease and usually occurs as unilateral or bilateral palpable masses. Primary breast amyloidosis presenting solely as microcalcifications is extremely rare. The authors report a case of a 73-year-old woman with persistent suspicious microcalcifications without palpable mass. The diagnosis was established by the presence of an amorphous and eosinophilic material that was positive for Congo red and dichroic under polarized light. Paraffin immunohistochemistry revealed the presence of kappa light chains (AL-type amyloidosis). The amyloid deposits were associated with microcalcifications. A complete work up was performed to exclude other localisations or associated pathologies and was negative. The primary breast amyloidosis is discussed and a review of the literature is presented.
引用
收藏
页码:177 / 180
页数:4
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