The use of allelic imbalance to ascertain cis-regulation for human UGT2B7 in vivo

被引：2
作者：
Wang, Pin-Yi [1 ,2 ]
Huo, Dezheng [3 ]
Sun, Chang [1 ,2 ,4 ]
Olopade, Olufunmilayo I. [4 ,5 ]
机构：
[1] Yunnan Univ, Lab Conservat & Utilizat Bioresources, Kunming 650091, Yunnan, Peoples R China
[2] Yunnan Univ, Minist Educ, Key Lab Microbial Div Southwest China, Kunming 650091, Yunnan, Peoples R China
[3] Univ Chicago, Dept Hlth Studies, Chicago, IL 60637 USA
[4] Univ Chicago, Dept Human Genet, Chicago, IL 60637 USA
[5] Univ Chicago, Dept Med, Ctr Clin Canc Genet, Chicago, IL 60637 USA
来源：
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 2013年 / 69卷 / 09期
关键词：
UDP-GLUCURONOSYLTRANSFERASES; MORPHINE GLUCURONIDATION; GENETIC POLYMORPHISMS; CANCER-PATIENTS; 2B7; EXPRESSION; PHARMACOGENOMICS; PROMOTER; UGT1A8; REGION;
D O I：
10.1007/s00228-013-1538-0
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1733 / 1735
页数：3
相关论文
共 23 条
[1]   Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects [J].
Chung, J-Y ;
Cho, J-Y ;
Yu, K-S ;
Kim, J-R ;
Lim, K. S. ;
Sohn, D-R ;
Shin, S-G ;
Jang, I-J .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (04) :595-600
[2]  
Coffman BL, 1997, DRUG METAB DISPOS, V25, P1
[3]   UGT pharmacogenomics: implications for cancer risk and cancer therapeutics [J].
Desai, AA ;
Innocenti, F ;
Ratain, MJ .
PHARMACOGENETICS, 2003, 13 (08) :517-523
[4]   Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on acyl-MPAG production in vitro and in adult renal transplant patients [J].
Djebli, Nassim ;
Picard, Nicolas ;
Rerolle, Jean-Philippe ;
Le Meur, Yann ;
Marquet, Pierre .
PHARMACOGENETICS AND GENOMICS, 2007, 17 (05) :321-330
[5]   A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity [J].
Duguay, Y ;
Báár, C ;
Skorpen, F ;
Guillemette, C .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 75 (03) :223-233
[6]   Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7 [J].
Gall, WE ;
Zawada, G ;
Mojarrabi, B ;
Tephly, TR ;
Green, MD ;
Coffman, BL ;
Mackenzie, PI ;
Radominska-Pandya, A .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1999, 70 (1-3) :101-108
[7]   Pharmacogenomics of human UDP-glucuronosyltransferase enzymes [J].
Guillemette, C .
PHARMACOGENOMICS JOURNAL, 2003, 3 (03) :136-158
[8]   Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene:: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients [J].
Holthe, M ;
Rakvåg, TN ;
Klepstad, P ;
Idle, JR ;
Kaasa, S ;
Krokan, HE ;
Skorpen, F .
PHARMACOGENOMICS JOURNAL, 2003, 3 (01) :17-26
[9]   Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy [J].
Holthe, M ;
Klepstad, P ;
Zahlsen, K ;
Borchgrevink, PC ;
Hagen, L ;
Dale, O ;
Kaasa, S ;
Krokan, HE ;
Skorpen, F .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2002, 58 (05) :353-356
[10]   Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene [J].
Innocenti, Federico ;
Liu, Wanqing ;
Fackenthal, Donna ;
Ramirez, Jacqueline ;
Chen, PeiXian ;
Ye, Xin ;
Wu, Xiaolin ;
Zhang, Wei ;
Mirkov, Snezana ;
Das, Soma ;
Cook, Edwin, Jr. ;
Ratain, Mark J. .
PHARMACOGENETICS AND GENOMICS, 2008, 18 (08) :683-697
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