Orthostatic Hypotension and Mortality in Elderly Frail Patients A Retrospective Cross-Sectional Study

被引:13
|
作者
Freud, Tamar [1 ]
Punchik, Boris [1 ,2 ,3 ]
Yan, Press [1 ,2 ,3 ]
机构
[1] Ben Gurion Univ Negev, Fac Hlth Sci, Siaal Res Ctr Family Med & Primary Care, Dept Family Med, Beer Sheva, Israel
[2] Clalit Hlth Serv, Yassky Clin, Unit Comprehens Geriatr Assessment, Beer Sheva, Israel
[3] Ben Gurion Univ Negev, Unit Community Geriatr, Div Hlth Community, IL-84105 Beer Sheva, Israel
关键词
MALMO PREVENTIVE PROJECT; COMPREHENSIVE GERIATRIC ASSESSMENT; POSTURAL BLOOD-PRESSURE; NURSING-HOME RESIDENTS; ALL-CAUSE MORTALITY; ATHEROSCLEROSIS RISK; PREDICTS MORTALITY; OLDER; METAANALYSIS; ASSOCIATION;
D O I
10.1097/MD.0000000000000977
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Orthostatic hypotension (OH) is a common problem in the elderly age group, and some studies have reported an association between OH and increased mortality. We evaluated possible associations between OH and mortality in a retrospective study of frail elderly patients who came for a comprehensive geriatric assessment. The study included all patients >= 65 years who were assessed in the outpatient Comprehensive Geriatric Assessment Unit. Data were collected from the computerized medical record, including blood pressure, sociodemographic data, lifestyle, falls, pulse rate, body mass index, functional and cognitive status, and comorbidity. Data on mortlaity were also collected. The study population consisted of 571 patients who underwent assessment over a 9-year study period. The mean age was 83.7 +/- 6.1, 35.9% were males, and 183 (32.1%) were diagnosed with OH. Systolic OH (OHS) was more common than diastolic OH (25.2% vs 15.6%). In univariate analyses, OHS was associated with increased overall mortality. Over the follow-up period, 30.2% of the OHS patients died compared with 22.3% (P = 0.037), but in the Cox models there was no statistically significant associations between OHS and overall mortality. In contrast, age, burden of comorbidity, a low high-density lipoprotein level, and low creatinine clearance were independent predictors of increased overall mortality. In a population of frail elderly patients with a high burden of comorbidity, OH was not an independent risk factor for overall mortality.
引用
收藏
页数:7
相关论文
共 50 条
  • [41] Pathways to Care for Patients with Depressive Disorder: A Retrospective Cross-Sectional Study
    Mandal, Saharab
    Sarkhel, Sujit
    Bhattacharya, Amit Kumar
    INDIAN JOURNAL OF PSYCHIATRY, 2025, 67 : S69 - S69
  • [42] POLYPHARMACY USE AMONG PATIENTS WITH DIABETES: A CROSS-SECTIONAL RETROSPECTIVE STUDY
    Alwhaibi, M.
    Balkhi, B.
    Alhawassi, T.
    Alkofide, H.
    Alduhaim, N.
    Alabdulali, R.
    Drweesh, H.
    Sambamoorthi, U.
    VALUE IN HEALTH, 2018, 21 : S71 - S71
  • [43] Prevalence of comorbid diseases in patients with fibromyalgia: A retrospective cross-sectional study
    Bilge, Ugur
    Sari, Yunus Emre
    Balcioglu, Huseyin
    Bilge, Nazife Sule Yasar
    Kasifoglu, Timucin
    Kayhan, Mehmet
    Unluoglu, Ilhami
    JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, 2018, 68 (05) : 729 - 732
  • [44] Correlation between depression and adherence to respiratory function exercise in elderly frail patients with tuberculosis: A cross-sectional survey
    Si, Qin
    Guo, Jing
    Feng, Yin-Ping
    Luo, Shui-Rong
    Liu, Zhong-Da
    Zhou, Guang-Nao
    MEDICINE, 2024, 103 (22) : E38212
  • [45] Ionized calcium level predicts in-hospital mortality of severe sepsis patients: A retrospective cross-sectional study
    Cekmen, Bora
    Koylu, Ramazan
    Akilli, Nazire Belgin
    Gunaydin, Yahya Kemal
    Koylu, Oznur
    Atis, Seref Emre
    Cander, Basar
    JOURNAL OF ACUTE DISEASE, 2021, 10 (06) : 247 - 251
  • [46] The prehospital quick SOFA score is associated with in-hospital mortality in noninfected patients: A retrospective, cross-sectional study
    Kitahara, Osamu
    Nishiyama, Kei
    Yamamoto, Bunsei
    Inoue, Shigeaki
    Inokuchi, Sadaki
    PLOS ONE, 2018, 13 (08):
  • [47] Factors associated with orthostatic hypotension in hospitalized elderly patients
    Guerin, Aline
    Bureau, Marie-Laure
    Ghazali, Nisrin
    Gervais, Raphaelle
    Liuu, Evelyne
    Seite, Florent
    Bellarbre, Fabienne
    Ingrand, Pierre
    Paccalin, Marc
    AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2016, 28 (03) : 513 - 517
  • [48] Efficacy of the Geriatric Trauma Outcome Score (GTOS) in Predicting Mortality in Trauma Patients: A Retrospective Cross-Sectional Study
    Huang, Ching-Ya
    Wu, Shao-Chun
    Lin, Tsan-Shiun
    Kuo, Pao-Jen
    Yang, Johnson Chia-Shen
    Hsu, Shiun-Yuan
    Hsieh, Ching-Hua
    DIAGNOSTICS, 2024, 14 (23)
  • [49] The influence of physical training status on postexercise hypotension in patients with hypertension: a cross-sectional study
    Imazu, Alexandre A.
    Goessler, Karla F.
    Casonatto, Juliano
    Polito, Marcos D.
    BLOOD PRESSURE MONITORING, 2017, 22 (04) : 196 - 201
  • [50] Factors associated with orthostatic hypotension in hospitalized elderly patients
    Aline Guérin
    Marie-Laure Bureau
    Nisrin Ghazali
    Raphaëlle Gervais
    Evelyne Liuu
    Florent Seité
    Fabienne Bellarbre
    Pierre Ingrand
    Marc Paccalin
    Aging Clinical and Experimental Research, 2016, 28 : 513 - 517