Mortality and Gram-negative rod bacteraemia in the intensive care unit

被引:11
作者
Gardiner, DF [1 ]
Scholand, SJ
Babinchak, T
机构
[1] Cornell Univ, Weill Med Coll, Div Int Med & Infect Dis, New York, NY 10021 USA
[2] Thomas Jefferson Univ Hosp, Div Infect Dis, Philadelphia, PA 19107 USA
[3] Wyeth Pharmaceut, Res & Dev, Collegeville, PA USA
关键词
bactaeremia; intensive care unit; mortality;
D O I
10.1016/j.jhin.2005.10.004
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This study identified 37 intensive care unit (ICU) patients with Gram-negative rod (GNR) bacteraemia. The sources, causative organisms and mortality of Gram-negative bacteraemia were consistent with historical series. Antibiotic resistance among well-described species with a propensity for antimicrobial resistance was the most common reason for ineffective antibiotic administration. This study emphasizes the importance of antibiotic resistance in antimicrobial selection and the power of Acute Physiology and Chronic Health Evaluation criteria for predicting patient mortality. (c) 2005 The Hospital. Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:453 / 457
页数:5
相关论文
共 20 条
[1]   Acinetobacter spp, as nosocomial pathogens: Microbiological, clinical, and epidemiological features [J].
BergogneBerezin, E ;
Towner, KJ .
CLINICAL MICROBIOLOGY REVIEWS, 1996, 9 (02) :148-+
[2]   DEFINITIONS FOR SEPSIS AND ORGAN FAILURE [J].
BONE, RC ;
SPRUNG, CL ;
SIBBALD, WJ .
CRITICAL CARE MEDICINE, 1992, 20 (06) :724-726
[3]   DEFINITIONS FOR SEPSIS AND ORGAN FAILURE AND GUIDELINES FOR THE USE OF INNOVATIVE THERAPIES IN SEPSIS [J].
BONE, RC ;
BALK, RA ;
CERRA, FB ;
DELLINGER, RP ;
FEIN, AM ;
KNAUS, WA ;
SCHEIN, RMH ;
SIBBALD, WJ .
CHEST, 1992, 101 (06) :1644-1655
[4]   ENTEROBACTER BACTEREMIA - CLINICAL-FEATURES AND EMERGENCE OF ANTIBIOTIC-RESISTANCE DURING THERAPY [J].
CHOW, JW ;
FINE, MJ ;
SHLAES, DM ;
QUINN, JP ;
HOOPER, DC ;
JOHNSON, MP ;
RAMPHAL, R ;
WAGENER, MM ;
MIYASHIRO, DK ;
YU, VL .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (08) :585-590
[5]   INFECTIONS DUE TO GRAM-NEGATIVE ORGANISMS - AN ANALYSIS OF 860 PATIENTS WITH BACTEREMIA AT UNIVERSITY OF MINNESOTA MEDICAL CENTER, 1958-1966 [J].
DUPONT, HL ;
SPINK, WW .
MEDICINE, 1969, 48 (04) :307-+
[6]   Has the mortality of septic shock changed with time? [J].
Friedman, G ;
Silva, E ;
Vincent, JL .
CRITICAL CARE MEDICINE, 1998, 26 (12) :2078-2086
[7]   Antibiotic susceptibility among aerobic gram-negative bacilli in intensive care units in 5 European countries [J].
Hanberger, H ;
Garcia-Rodriguez, JA ;
Gobernado, M ;
Goossens, H ;
Nilsson, LE ;
Struelens, MJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 281 (01) :67-71
[8]   APACHE-II - A SEVERITY OF DISEASE CLASSIFICATION-SYSTEM [J].
KNAUS, WA ;
DRAPER, EA ;
WAGNER, DP ;
ZIMMERMAN, JE .
CRITICAL CARE MEDICINE, 1985, 13 (10) :818-829
[9]   THE APACHE-III PROGNOSTIC SYSTEM - RISK PREDICTION OF HOSPITAL MORTALITY FOR CRITICALLY ILL HOSPITALIZED ADULTS [J].
KNAUS, WA ;
WAGNER, DP ;
DRAPER, EA ;
ZIMMERMAN, JE ;
BERGNER, M ;
BASTOS, PG ;
SIRIO, CA ;
MURPHY, DJ ;
LOTRING, T ;
DAMIANO, A ;
HARRELL, FE .
CHEST, 1991, 100 (06) :1619-1636
[10]   Inadequate antimicrobial treatment of infections - A risk factor for hospital mortality among critically ill patients [J].
Kollef, MH ;
Sherman, G ;
Ward, S ;
Fraser, VJ .
CHEST, 1999, 115 (02) :462-474