Are the EI escorial and revised EI escorial criteria for ALS reproducible? A study of inter-observer agreement

被引:23
作者
Forbes, RB [1 ]
Colville, S [1 ]
Swingler, RJ [1 ]
机构
[1] Univ Dundee, Ninewells Hosp & Med Sch, Scottish Motor Neuron Dis Register, Dundee DD1 9SY, Scotland
来源
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS | 2001年 / 2卷 / 03期
关键词
amyotrophic lateral sclerosis; El Escorial criteria; observer agreement; kappa statistic;
D O I
10.1080/146608201753275472
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
INTRODUCTION: For accurate diagnosis, inter-observer agreement of criteria is important. METHODS: Using case records, the reproducibility of the original and revised EI Escorial diagnostic criteria for amyotrophic lateral sclerosis were tested in a consecutive series of people referred to the Scottish Motor Neuron Disease Register. RESULTS: Agreement between independent observers was similar (weighted kappa: 0.783, 95% CI 0.656 to 0.991 (original criteria), 0.681, 95% CI 0.485 to 0.878 (revised)). CONCLUSIONS: Serious errors are unlikely, but the revised criteria may be less reproducible as they include more diagnostic categories. Revisions of diagnostic criteria should be tested for reproducibility and validity prior to widespread adoption.
引用
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页码:135 / 138
页数:4
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