An intramolecular [2+2] photocycloaddition-fragmentation approach towards the total synthesis of asteriscanolide

被引：22

作者：

BookerMilburn, KI

Cowell, JK

机构：

[1] School of Chemical Sciences, University of East Anglia, Norwich, Norfolk

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 13期

关键词：

D O I：

10.1016/0040-4039(96)00224-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new route towards the Asteriscanolide skeleton is described. The key features include an efficient intramolecular [2+2] photocycloaddition of the alpha,beta-unsaturated acid-ether 10 followed by a Curtins rearrangement/ ruthenium tetroxide/fragmentation sequence to yield the cyclooctane lactones 13 and 14.

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页码：2177 / 2180

页数：4

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