Synchrotron Radiation in Life Sciences

被引:3
作者
Stojanoff, Vivian [1 ]
Northrup, Paul [2 ]
Pietri, Ruth [1 ]
Zhong, Zhong [1 ]
机构
[1] Brookhaven Natl Lab, Upton, NY 11973 USA
[2] SUNY Stony Brook, Stony Brook, NY 11794 USA
关键词
Synchrotron Radiation; macromolecular crystallography; spectroscopy; x-ray diffraction; x-ray imaging; PROTEIN CRYSTALS; MACROMOLECULAR CRYSTALLOGRAPHY; SPECTROSCOPIC METHODS; BIOLOGICAL CRYSTALS; POWDER DIFFRACTION; LYSOZYME CRYSTALS; CELLULAR-LEVEL; DYNAMICS; TOMOGRAPHY; TOPOGRAPHY;
D O I
10.2174/092986612800793163
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Synchrotron Radiation (SR) presents itself as a "play-ground" with a large range of methods and techniques suitable to unveil the mysteries of life. Here we attempt to present a few of these methods that complement those employed in the home laboratory. SR diffraction, spectroscopy and imaging methods relevant to the atomic structure determination and characterization of the properties and function of chemical compounds and macromolecules of biological relevance, are introduced.
引用
收藏
页码:761 / 769
页数:9
相关论文
共 80 条
[1]  
ANDERSEN EH, 1999, NANOFABRICATION XRAY
[2]   Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein [J].
Anderson, S ;
Srajer, V ;
Pahl, R ;
Rajagopal, S ;
Schotte, F ;
Anfinrud, P ;
Wulff, M ;
Moffat, K .
STRUCTURE, 2004, 12 (06) :1039-1045
[3]  
Attwood D., 1999, SOFT XRAYS EXTREME U
[4]   Features of the secondary structure of a protein molecule from powder diffraction data [J].
Basso, Sebastian ;
Besnard, Celine ;
Wright, Jonathan P. ;
Margiolaki, Irene ;
Fitch, Andrew ;
Pattison, Philip ;
Schiltz, Marc .
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2010, 66 :756-761
[5]   Synchrotron X-ray reciprocal-space mapping, topography and diffraction resolution studies of macromolecular crystal quality [J].
Boggon, TJ ;
Helliwell, JR ;
Judge, RA ;
Olczak, A ;
Siddons, DP ;
Snell, EH ;
Stojanoff, V .
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2000, 56 :868-880
[6]   Soluble Synthetic Analogues of Malaria Pigment: Structure of Mesohematin Anhydride and its Interaction with Chloroquine in Solution [J].
Bohle, D. Scott ;
Dodd, Erin L. ;
Kosar, Aaron J. ;
Sharma, Lauren ;
Stephens, Peter W. ;
Suarez, Liliana ;
Tazoo, Dagobert .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (27) :6151-6154
[7]   AMO instrumentation for the LCLS X-ray FEL [J].
Bozek, J. D. .
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS, 2009, 169 :129-132
[8]   Femtosecond XANES Study of the Light-Induced Spin Crossover Dynamics in an Iron(II) Complex [J].
Bressler, Ch. ;
Milne, C. ;
Pham, V. -T. ;
ElNahhas, A. ;
van der Veen, R. M. ;
Gawelda, W. ;
Johnson, S. ;
Beaud, P. ;
Grolimund, D. ;
Kaiser, M. ;
Borca, C. N. ;
Ingold, G. ;
Abela, R. ;
Chergui, M. .
SCIENCE, 2009, 323 (5913) :489-492
[9]   Molecular Structural Dynamics Probed by Ultrafast X-Ray Absorption Spectroscopy [J].
Bressler, Christian ;
Chergui, Majed .
ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 61, 2010, 61 :263-282
[10]  
Caliandro R, 2008, POWDER DIFFRACTION: THEORY AND PRACTICE, P227, DOI 10.1039/9781847558237-00227