Degradable "click" polyesters from erythritol having free hydroxyl groups

被引：17

作者：

Bueno, Manuel ^{[1
]}

Molina, Inmaculada ^{[1
]}

Galbis, Juan A. ^{[1
]}

机构：

[1] Univ Seville, Fac Farm, Dept Quim Organ & Farmaceut, E-41012 Seville, Spain

来源：

POLYMER DEGRADATION AND STABILITY | 2012年 / 97卷 / 09期

关键词：

Click polymerization; Hydrophilic polymers; Water-soluble polymers; Polyesters; Hydrolytic degradation; AZIDE-ALKYNE CYCLOADDITION; STEP-GROWTH POLYMERIZATION; 1,3-DIPOLAR CYCLOADDITIONS; POLY(ETHYLENE GLYCOL); TRIAZOLE-OLIGOMERS; TERMINAL ALKYNES; METAL-FREE; CHEMISTRY; POLYMERS; COPPER;

D O I：

10.1016/j.polymdegradstab.2012.06.020

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Click Cu(l)-catalysed polymerization and thermal polyaddition of diynes having ester linkages and 1,4-diazido-1,4-dideoxyerythritol were performed to obtain polyesters containing 1,2,3-triazole rings along the polymer chain. The resulting polyesters had weight-average molecular weights in the 13,000-37,000 range. Thermal studies revealed them to be mainly amorphous and stable up to 250 degrees C under nitrogen. The polymers are hydrophilic, several of them being water-soluble. Degradation studies of a water-soluble prototype polymer showed they are hydrolytically degradable. These studies were carried out at 37 degrees C in doubly distilled water and buffered salt solution at pH 7.4, and were monitored by GPC, and IR and NMR spectroscopies. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1662 / 1670

页数：9

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