Donor age in living donor liver transplantation

被引：24
作者：
Ikegami, T. [1 ,2 ]
Taketomi, A. [1 ]
Ohta, R. [1 ]
Soejima, Y. [1 ]
Yoshizumi, T. [1 ]
Shimada, M. [2 ]
Maehara, Y. [1 ]
机构：
[1] Kyushu Univ, Dept Surg & Sci, Grad Sch Med Sci, Fukuoka 8128582, Japan
[2] Univ Tokushima, Dept Surg, Tokushima 770, Japan
来源：
TRANSPLANTATION PROCEEDINGS | 2008年 / 40卷 / 05期
关键词：
D O I：
10.1016/j.transproceed.2008.02.084
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Background. We sought to elucidate the influence of donor age in living donor liver transplantation (LDLT) using either left lobe (LL) or right lobe (RL) grafts. Methods. Recipients (n = 232) were categorized as: group O/LL (LL, donor age >50, n = 20); group Y/LL (LL, donor age <= 50, n = 140); Group O/RL (RL, donor age >50, n = 12); and group Y/RL (RL, donor age <= 50, n = 61). We compared post-LDLT graft functions. Results. Among LL LDLT, the incidence of small-for-size syndrome was significantly greater for group O/LL compared with group Y/LL (60.0% vs 16.3%, P < .01). However, the cumulative 5-year graft survivals were 73.8% in group 0 and 76.7% in group Y without substantial difference. In RL LDLT, the post-LDLT morbidity and mortality were similar for group O/RL and group Y/RL. Conclusion. Partial liver grafts, even though LL grafts, from older donors can be used safely with caution in LDLT.
引用
收藏
页码：1471 / 1475
页数：5
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