Melissa officinalis L. subsp altissima (Sibth. & Sm.) Arcang. essential oil: Chemical composition and preliminary antimicrobial investigation of samples obtained at different harvesting periods and by fractionated extractions

被引:21
作者
Bozovic, Mijat [1 ,2 ]
Garzoli, Stefania [3 ]
Baldisserotto, Anna [4 ]
Romagnoli, Carlo [5 ]
Pepi, Federico [3 ]
Cesa, Stefania [3 ]
Vertuani, Silvia [4 ]
Manfredini, Stefano [4 ]
Ragno, Rino [2 ,3 ,6 ]
机构
[1] Univ Montenegro, Fac Nat Sci & Math, Dzordza Vasingtona Bb, Podgorica 81000, Montenegro
[2] Sapienza Univ, Rome Ctr Mol Design, Dept Drug Chem & Technol, Ple Aldo Moro 5, I-00185 Rome, Italy
[3] Sapienza Univ, Dept Drug Chem & Technol, Ple Aldo Moro 5, I-00185 Rome, Italy
[4] Univ Ferrara, Dept Life Sci & Biotechnol, Via L Borsari 46, I-44121 Ferrara, Italy
[5] Dept Life Sci, Viale Caduti Guerra 127, I-41121 Modena, Italy
[6] Alchem Dynam Srl, I-00125 Rome, Italy
关键词
24-h steam distillation; Melissa officinalis L. subsp altissima (Sibth. & Sm.) arcang; cis-caryophyllene; Caryophyllene oxide; VOLATILE CONSTITUENTS; LEMON BALM; IRAN; LEAVES; PHYTOCHEMISTRY; LAMIACEAE; FLOWER; TURKEY; SERBIA; BENTH;
D O I
10.1016/j.indcrop.2018.03.018
中图分类号
S2 [农业工程];
学科分类号
0828 ;
摘要
A comprehensive study on essential oils extracted from different samples of Melissa officinalis L. subsp. altissima (Sibth. & Sm.) Arcang. (Lamiaceae) collected in Tarquinia (Italy) is reported. In this study, the 24-h steam distillation procedure for essential oil preparation, in terms of different harvesting periods and extraction times was applied. The GC/MS analysis showed cis-caryophyllene and its oxide as the major essential oil's constituents. A great impact of phenological stage on chemical profile of essential oil was observed. Regarding the duration of the extraction process, prolonged distillation led to chemically more diverse oil samples. Preliminary microbiological evaluations of the essential oils samples revealed the lack of significant efficacy against Candida albicans.
引用
收藏
页码:317 / 321
页数:5
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