Development and definition of a simplified scanning procedure and scoring method for Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US)

被引：209
作者：
Martinoli, Carlo [1 ]
Alberighi, Ornella Della Casa [3 ]
Di Minno, Giovanni [5 ]
Graziano, Ermelinda [6 ]
Molinari, Angelo Claudio [4 ]
Pasta, Gianluigi [7 ]
Russo, Giuseppe [1 ]
Santagostino, Elena [8 ]
Tagliaferri, Annarita [9 ]
Tagliafico, Alberto [2 ]
Morfini, Massimo [10 ]
机构：
[1] Univ Genoa, Radiol DISSAL, Genoa, Italy
[2] Univ Genoa, Ist Anat Umana DIMES, Genoa, Italy
[3] IRCCS Ist G Gaslini, Direz Sci Unita Farmacol Clin & Sperimentaz Clin, Genoa, Italy
[4] Unita Trombosi & Emostasi IRCCS Ist G Gaslini, Genoa, Italy
[5] Univ Naples Federico II, Dipartimento Med Clin & Sperimentale, I-80138 Naples, Italy
[6] Univ G dAnnunzio, Dipartimento Med Sci Invecchiamento, Chieti, Italy
[7] Policlin Univ Milano, Dipartimento Ortopedia, Milan, Italy
[8] Policlin Univ Milano, Ctr Emofila & Trombosi AB Bonomi, Milan, Italy
[9] Dipartimento Med Interna AOU Parma, Parma, Italy
[10] Ctr Emofilia AOU Careggi Firenze, Florence, Italy
来源：
THROMBOSIS AND HAEMOSTASIS | 2013年 / 109卷 / 06期
关键词：
Haemophilic arthropathy; joints; scoring systems; ultrasonography; synovitis; osteochondral damage; SONOGRAPHY; SYNOVITIS;
D O I：
10.1160/TH12-11-0874
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The aim of this study was to develop a simplified ultrasound scanning procedure and scoring method, named Haemophilia Early Arthropathy Detection with UltraSound [HEAD-US], to evaluate joints of patients, with haemophilic arthropathy. After an initial consensus-based pro, cess involving a multidisciplinary panel of experts, three comprehensive and evidence-based US scanning procedures to image the elbow, knee and ankle were established with the aim to increase sensitivity in detection of early signs of joint involvement while keeping the technique easy and quick to perform. Each procedure included systematic evaluation of synovial recesses and selection of a single osteochondral surface for damage analysis. Based on expert consensus, a simplified scoring system based on an additive scale was created to define the joint status and, in perspective, to offer a tool to evaluate disease progression and monitor the result of treatment in follow-up studies.
引用
收藏
页码：1170 / 1179
页数：10
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