Focused Fluorescent Probe Library for Metal Cations and Biological Anions

被引：16

作者：

Rhee, Hyun-Woo ^{[1
]}

Lee, Sang Wook ^{[1
]}

Lee, Jun-Seok ^{[2
]}

Chang, Young-Tae ^{[2
]}

Hong, Jong-In ^{[1
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea

[2] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

来源：

ACS COMBINATORIAL SCIENCE | 2013年 / 15卷 / 09期

关键词：

fluorescent probe library; metal cations; biological anions; thymidine; AQUEOUS-SOLUTION; SENSOR; CHEMOSENSORS; CADMIUM; RELEASE; MERCURY; LOGIC; CELLS; CD2+; PET;

D O I：

10.1021/co400034x

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent probes were screened for identifying an ultraselective probe for dTTP.

引用

页码：483 / 490

页数：8

共 47 条

[1] Zinc-nucleic acid interaction [J].

Aoki, S ;

Kimura, E .

CHEMICAL REVIEWS, 2004, 104 (02) :769-787

[2] A selective reaction-based fluorescent probe for detecting cobalt in living cells [J].

Au-Yeung, Ho Yu ;

New, Elizabeth J. ;

Chang, Christopher J. .

CHEMICAL COMMUNICATIONS, 2012, 48 (43) :5268-5270

[3]

Berg J.M., 2002, Biochemistry

[4] Bringing chemistry to life [J].

Boyce, Michael ;

Bertozzi, Carolyn R. .

NATURE METHODS, 2011, 8 (08) :638-642

[5] Selective Manipulation of ICT and PET Processes in Styryl-Bodipy Derivatives: Applications in Molecular Logic and Fluorescence Sensing of Metal Ions [J].

Bozdemir, O. Altan ;

Guliyev, Ruslan ;

Buyukcakir, Onur ;

Selcuk, Sencer ;

Kolemen, Safacan ;

Gulseren, Gulcihan ;

Nalbantoglu, Tugrul ;

Boyaci, Hande ;

Akkaya, Engin U. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (23) :8029-8036

[6] Reaction-Based Sensing of Fluoride Ions Using Built-in Triggers for Intramolecular Charge Transfer and Photoinduced Electron Transfer [J].

Bozdemir, O. Altan ;

Sozmen, Fazli ;

Buyukcakir, Onur ;

Guliyev, Ruslan ;

Cakmak, Yusuf ;

Akkaya, Engin U. .

ORGANIC LETTERS, 2010, 12 (07) :1400-1403

[7] A Highly Selective Pyrophosphate Sensor Based on ESIPT Turn-On in Water [J].

Chen, Wei-Hua ;

Xing, Yu ;

Pang, Yi .

ORGANIC LETTERS, 2011, 13 (06) :1362-1365

[8] A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell [J].

Cheng, Tanyu ;

Xu, Yuifang ;

Zhang, Shenyi ;

Zhu, Weiping ;

Qian, Xuhong ;

Duan, Liping .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (48) :16160-+

[9] A Selective Colorimetric Hg2+ Probe Featuring a Styryl Dithiaazacrown Containing Platinum(II) Terpyridine Complex through Modulation of the Relative Strength of ICT and MLCT Transitions [J].

Chung, Sung-Kuang ;

Tseng, Yong-Ren ;

Chen, Chan-Yu ;

Sun, Shih-Sheng .

INORGANIC CHEMISTRY, 2011, 50 (07) :2711-2713

[10] Effective PET and ICT switching of boradiazaindacene emission: A unimolecular, emission-mode, molecular half-subtractor with reconfigurable logic gates [J].

Coskun, A ;

Deniz, E ;

Akkaya, EU .

ORGANIC LETTERS, 2005, 7 (23) :5187-5189

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