Focused Fluorescent Probe Library for Metal Cations and Biological Anions

被引:16
|
作者
Rhee, Hyun-Woo [1 ]
Lee, Sang Wook [1 ]
Lee, Jun-Seok [2 ]
Chang, Young-Tae [2 ]
Hong, Jong-In [1 ]
机构
[1] Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea
[2] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore
关键词
fluorescent probe library; metal cations; biological anions; thymidine; AQUEOUS-SOLUTION; SENSOR; CHEMOSENSORS; CADMIUM; RELEASE; MERCURY; LOGIC; CELLS; CD2+; PET;
D O I
10.1021/co400034x
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent probes were screened for identifying an ultraselective probe for dTTP.
引用
收藏
页码:483 / 490
页数:8
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