Characterization of Phenolic Constituents from Ephedra Herb Extract

被引：49

作者：

Amakura, Yoshiaki ^{[1
]}

Yoshimura, Morio ^{[1
]}

Yamakami, Saori ^{[1
]}

Yoshida, Takashi ^{[1
]}

Wakana, Daigo ^{[2
]}

Hyuga, Masashi ^{[3
]}

Hyuga, Sumiko ^{[4
]}

Hanawa, Toshihiko ^{[4
]}

Goda, Yukihiro ^{[2
]}

机构：

[1] Matsuyama Univ, Dept Pharmacognosy, Coll Pharmaceut Sci, Matsuyama, Ehime 7908578, Japan

[2] Natl Inst Hlth Sci, Div Pharmacognosy Phytochem & Narcot, Setagaya Ku, Tokyo 1588501, Japan

[3] Natl Inst Hlth Sci, Div Biol Chem & Biol, Setagaya Ku, Tokyo 1588501, Japan

[4] Kitasato Univ, Oriental Med Res Ctr, Dept Clin Res, Minato Ku, Tokyo 1088642, Japan

来源：

MOLECULES | 2013年 / 18卷 / 05期

关键词：

Ephedra herb; herbacetin; 7-O-neohesperidoside; phenolics; Mao; Kampo;

D O I：

10.3390/molecules18055326

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nine known compounds: trans-cinnamic acid, catechin, syringin, epicatechin, symplocoside, kaempferol 3-O-rhamnoside 7-O-glucoside, isovitexin 2-O-rhamnoside, herbacetin 7-O-glucoside, and pollenitin B and a new flavonoid glycoside, characterized as herbacetin 7-O-neohesperidoside (1) on the basis of spectroscopic analysis and chemical evidence, were isolated from a traditional crude drug, "Ephedra herb extract". Compound 1 had no effects on HGF-induced motility, whereas herbacetin, which is an aglycone of 1, significantly inhibited it.

引用

页码：5326 / 5334

页数：9

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