Comparison of contrast in brightness mode and strain ultrasonography of glial brain tumours

被引:33
作者
Selbekk, Tormod [1 ,2 ]
Brekken, Reidar [1 ,2 ]
Indergaard, Marit [2 ]
Solheim, Ole [2 ,3 ]
Unsgard, Geirmund [2 ,3 ]
机构
[1] SINTEF, Dept Med Technol, N-7034 Trondheim, Norway
[2] Norwegian Univ Sci & Technol, Fac Med, N-7034 Trondheim, Norway
[3] St Olavs Univ Hosp, Dept Neurosurg, Trondheim, Norway
关键词
Ultrasound; Elastography; Elastogram; Strain; Brain; Neurosurgery; Brain tumours; Image contrast; ULTRASOUND; BENIGN;
D O I
10.1186/1471-2342-12-11
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Background: Image contrast between normal tissue and brain tumours may sometimes appear to be low in intraoperative ultrasound. Ultrasound imaging of strain is an image modality that has been recently explored for intraoperative imaging of the brain. This study aims to investigate differences in image contrast between ultrasound brightness mode (B-mode) images and ultrasound strain magnitude images of brain tumours. Methods: Ultrasound radiofrequency (RF) data was acquired during surgery in 15 patients with glial tumours. The data were subsequently processed to provide strain magnitude images. The contrast in the B-mode images and the strain images was determined in assumed normal brain tissue and tumour tissue at selected regions of interest (ROI). Three measurements of contrast were done in the ultrasound data for each patient. The B-mode and strain contrasts measurements were compared using the paired samples t- test. Results: The statistical analysis of a total of 45 measurements shows that the contrasts in the strain magnitude images are significantly higher than in the conventional ultrasound B-mode images (P < 0.0001). Conclusions: The results indicate that ultrasound strain imaging provides better discrimination between normal brain tissue and glial tumour tissue than conventional ultrasound B-mode imaging. Ultrasound imaging of tissue strain therefore holds the potential of becoming a valuable adjunct to conventional intraoperative ultrasound imaging in brain tumour surgery.
引用
收藏
页数:7
相关论文
共 14 条
[1]   Differentiating benign from malignant solid breast masses with US strain imaging [J].
Burnside, Elizabeth S. ;
Hall, Timothy J. ;
Sommer, Amy M. ;
Hesley, Gina K. ;
Sisney, Gale A. ;
Svensson, William E. ;
Fine, Jason P. ;
Jiang, Jinfeng ;
Hangiandreou, Nicholas J. .
RADIOLOGY, 2007, 245 (02) :401-410
[2]   A NOTE ON THE APPLICATION OF THE HILBERT TRANSFORM TO TIME-DELAY ESTIMATION [J].
CABOT, RC .
IEEE TRANSACTIONS ON ACOUSTICS SPEECH AND SIGNAL PROCESSING, 1981, 29 (03) :607-609
[3]  
Cho N, 2010, J ULTRAS MED, V29, P1
[4]   Utility of elastography for differential diagnosis of benign and malignant thyroid nodules [J].
Kagoya, Ryoji ;
Monobe, Hiroko ;
Tojima, Hitoshi .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2010, 143 (02) :230-234
[5]   AN AXIAL VELOCITY ESTIMATOR FOR ULTRASOUND BLOOD-FLOW IMAGING, BASED ON A FULL EVALUATION OF THE DOPPLER EQUATION BY MEANS OF A 2-DIMENSIONAL AUTOCORRELATION APPROACH [J].
LOUPAS, T ;
POWERS, JT ;
GILL, RW .
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 1995, 42 (04) :672-688
[6]   Vibrography during tumor neurosurgery [J].
Scholz, M ;
Noack, V ;
Pechlivanis, I ;
Engelhardt, M ;
Fricke, B ;
Linstedt, U ;
Brendel, B ;
Schmieder, K ;
Ermert, H ;
Harders, A .
JOURNAL OF ULTRASOUND IN MEDICINE, 2005, 24 (07) :985-992
[7]   Strain processing of intraoperative ultrasound images of brain tumours: Initial results [J].
Selbekk, T ;
Bang, J ;
Unnsgaard, G .
ULTRASOUND IN MEDICINE AND BIOLOGY, 2005, 31 (01) :45-51
[8]   TISSUE MOTION AND STRAIN IN THE HUMAN BRAIN ASSESSED BY INTRAOPERATIVE ULTRASOUND IN GLIOMA PATIENTS [J].
Selbekk, Tormod ;
Brekken, Reidar ;
Solheim, Ole ;
Lydersen, Stian ;
Hernes, Toril A. N. ;
Unsgaard, Geirmund .
ULTRASOUND IN MEDICINE AND BIOLOGY, 2010, 36 (01) :2-10
[9]   Two-dimensional temperature estimation using diagnostic ultrasound [J].
Simon, C ;
VanBaren, P ;
Ebbini, ES .
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 1998, 45 (04) :1088-1099
[10]   Significant Differentiation of Focal Breast Lesions Calculation of Strain Ratio in Breast Sonoelastography [J].
Thomas, Anke ;
Degenhardt, Friedrich ;
Farrokh, Andre ;
Wojcinski, Sebastian ;
Slowinski, Torsten ;
Fischer, Thomas .
ACADEMIC RADIOLOGY, 2010, 17 (05) :558-563