Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry

被引：21

作者：

Crow, Brian ^{[1
]}

Bishop, Michael ^{[1
]}

Paliakov, Ekaterina ^{[1
]}

Norton, Dean ^{[1
]}

George, Joe ^{[1
]}

Bralley, J. Alexander ^{[1
]}

机构：

[1] Metametrix Clin Lab, Duluth, GA 30096 USA

来源：

BIOMEDICAL CHROMATOGRAPHY | 2008年 / 22卷 / 12期

关键词：

aromatic acids; LC-MS/MS; biomarkers;

D O I：

10.1002/bmc.1064

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The separation and detection of 11 urinary aromatic acids was developed using HPLC-MS/MS. The method features a simple sample preparation involving a single-step dilution with internal standard and a rapid 8 min chromatographic separation. The accuracy was evaluated by the recovery of known spikes between 87 and 110%. Inter- and intra-assay precision (CV) was below 11% in all cases and the analytes were observed to be stable for up to 8 weeks when stored at -20 degrees C. The method was validated based upon linearity, accuracy, precision and stability and was used to establish reference intervals for children and adults. Copyright (C) 2008 John Wiley & Sons, Ltd.

引用

收藏

页码：1346 / 1353

页数：8

相关论文

共 50 条

[31] Determination of bile acids in biological fluids by liquid chromatography-electrospray tandem mass spectrometry [J].

Perwaiz, S ;

Tuchweber, B ;

Mignault, D ;

Gilat, T ;

Yousef, IM .

JOURNAL OF LIPID RESEARCH, 2001, 42 (01) :114-119

[32] Rapid quantification of murine bile acids using liquid chromatography-tandem mass spectrometry [J].

Hermeling, Sven ;

Plagge, Johannes ;

Krautbauer, Sabrina ;

Ecker, Josef ;

Burkhardt, Ralph ;

Liebisch, Gerhard .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2025, 417 (04) :687-696

[33] Untargeted screening of urinary peptides with liquid chromatography coupled to hybrid linear-ion trap tandem mass spectrometry [J].

Sauvage, Francois-Ludovic ;

Gastinel, Louis Noel ;

Marquet, Pierre .

JOURNAL OF CHROMATOGRAPHY A, 2012, 1259 :138-147

[34] Study of sample preparation for quantitative analysis of amino acids in human sweat by liquid chromatography-tandem mass spectrometry [J].

Delgado-Povedano, M. M. ;

Calderon-Santiago, M. ;

Priego-Capote, F. ;

Luque de Castro, M. D. .

TALANTA, 2016, 146 :310-317

[35] A liquid chromatography tandem mass spectrometry method for plasma glucagon [J].

Nguyen, Van Long ;

Tuckwell, Phillip ;

Ireland, Andrea ;

Fitzpatrick, Michael .

ANALYTICAL BIOCHEMISTRY, 2023, 675

[36] Determination of mycotoxins in cereals by liquid chromatography tandem mass spectrometry [J].

Soleimany, F. ;

Jinap, S. ;

Abas, F. .

FOOD CHEMISTRY, 2012, 130 (04) :1055-1060

[37] Pain Management Testing by Liquid Chromatography Tandem Mass Spectrometry [J].

Bodor, Geza S. .

CLINICS IN LABORATORY MEDICINE, 2018, 38 (03) :455-+

[38] Analysis of primary aromatic amines in the mainstream waterpipe smoke using liquid chromatography-electrospray ionization tandem mass spectrometry [J].

Schubert, Jens ;

Kappenstein, Oliver ;

Luch, Andreas ;

Schulz, Thomas G. .

JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (33) :5628-5637

[39] Development and validation of a liquid chromatography tandem mass spectrometry method for the measurement of urinary catecholamines in diagnosis of pheochromocytoma [J].

Shen, Ying ;

Cheng, Liming ;

Guan, Qing ;

Li, Huijun ;

Lu, Jie ;

Wang, Xu .

BIOMEDICAL CHROMATOGRAPHY, 2017, 31 (11)

[40] Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry [J].

Hallin, Erik I. ;

Serkland, Trond Traetteberg ;

Myhr, Kjell-Morten ;

Torkildsen, Oivind Grytten ;

Skrede, Silje .

JOURNAL OF MASS SPECTROMETRY AND ADVANCES IN THE CLINICAL LAB, 2022, 25 :53-60

← 1 2 3 4 5 →