Exposure of the human brain to an electromagnetic plane wave in the 100-1000 MHz frequency range for potential treatment of neurodegenerative diseases

Radio signals can induce an electric field inside the brain, which might be potentially beneficial in the treatment of neurodegenerative diseases. For instance, a new method for the treatment of Alzheimer's disease in mice through the exposure to the radiation of mobile phones has been successfully demonstrated. In the light of these results, studying the induction of an electric field in the human brain through the controlled exposure to radio signals is of paramount importance for the eventual development of similar treatment techniques in humans. In this study, the authors study the radio signals in 100-1000 MHz as a means for inducing an electric field into the human brain in a non-invasive fashion. A voxel representation of the human body was used for numerical simulations, and the induced electric fields in the brain tissues (white and grey matters) were calculated for different incoming wave polarisations. A quantitative measure of the electric field inside the brain tissues is presented together with the average specific absorption rate. It is shown that the average electric field intensity in the brain has two local maxima at 300 and 600 MHz. These results are important for defining the optimal frequency band and wave polarisation.