Hypertension as a paraneoplastic syndrome in hepatocellular carcinoma

被引：16

作者：

Arai, H ^{[1
]}

Saitoh, S ^{[1
]}

Matsumoto, T ^{[1
]}

Makita, F ^{[1
]}

Mitsugi, S ^{[1
]}

Yuasa, K ^{[1
]}

Takagi, H ^{[1
]}

Mori, M ^{[1
]}

机构：

[1] Natl Sanatorium Nishi Gunma Hosp, Dept Internal Med, Shibukawa, Japan

来源：

JOURNAL OF GASTROENTEROLOGY | 1999年 / 34卷 / 04期

关键词：

angiotensin; hepatocellular carcinoma; paraneoplastic syndrome;

D O I：

10.1007/s005350050309

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We report a 66-year-old man with hepatocellular carcinoma who was positive for hepatitis B surface antigen, and was hospitalized because of hypoglycemia and hypertension. His plasma renin activity was normal (2.3ng/ml per h), but concentrations of angiotensin I (>2500pg/ml) and II (86pg/ml) were high. Increased angiotensin I level at sites proximal and distal from the confluence of the hepatic vein and the inferior vena cava indicated that the hypertension was provoked by overproduction of angiotensin I from the hepatocellular carcinoma. Previous reports of patients with hepatocellular carcinoma with hypertension due to abnormality of renin-angiotensin system are reviewed.

引用

页码：530 / 534

页数：5