Treatment of the axilla in patients with primary breast cancer and low burden axillary disease: Limitations of the evidence from randomised controlled trials

被引：9
作者：
Robertson, J. F. R. [1 ]
Herrod, P. J. J. [1 ]
Matthew, J. [2 ]
Kilburn, L. S. [3 ]
Coles, C. E. [4 ]
Bradbury, I. [5 ]
机构：
[1] Univ Nottingham, Royal Derby Hosp, Fac Med & Hlth Sci, Uttoxeter Rd, Derby DE22 3DT, England
[2] Peterborough City Hosp, Dept Surg, Peterborough, Cambs, England
[3] Inst Canc Res, London, England
[4] Addenbrookes Hosp, Dept Oncol, Cambridge, England
[5] Frontier Sci Scotland, Kincraig, Scotland
来源：
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2017年 / 110卷
关键词：
Breast cancer; Axilla; Surgery; LYMPH-NODE DISSECTION; SENTINEL-NODE; INTERNAL MAMMARY; CLINICAL-TRIAL; RADIOTHERAPY; IRRADIATION; THERAPY; SURGERY; WOMEN; Z0011;
D O I：
10.1016/j.critrevonc.2016.11.011
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Invasive breast cancer is the second most common cancer worldwide. It is known to metastasise to the regional axillary lymph nodes but there has been debate over what is the best way to stage and treat the axilla in patients presenting with primary breast cancer. Multiple trials over the last two decades have led to a change in practice from routine axillary lymph node dissection to sentinel lymph node biopsy in patients who are clinically lymph node negative preoperatively. This has resulted in new questions regarding subsequent treatment of some patients. This review will critically appraise the evidence on axillary treatment in patients with low burden axillary disease and highlight limitations of relevant randomised controlled trials. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：74 / 80
页数：7
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