Preventing Pancreatitis by Protecting the Mitochondrial Permeability Transition Pore

被引：7
作者：
Lerch, Markus M. [1 ]
Halangk, Walter [2 ]
Mayerle, Julia
机构：
[1] Univ Med Greifswald, Dept Med A, D-17475 Greifswald, Germany
[2] Otto Von Guericke Univ, Dept Surg, Magdeburg, Germany
来源：
GASTROENTEROLOGY | 2013年 / 144卷 / 02期
关键词：
ZYMOGEN ACTIVATION; VACUOLE FORMATION; CALCIUM; TRYPSINOGEN; ALCOHOL; SECRETION; PREMATURE; CERULEIN; RELEASE; REGION;
D O I：
10.1053/j.gastro.2012.12.010
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：265 / 269
页数：6
相关论文
共 33 条
[1]   Fatty acid ethyl esters-alcohol's Henchmen in the pancreas? [J].
Apte, MV ;
Pirola, RC ;
Wilson, JS .
GASTROENTEROLOGY, 2006, 130 (03) :992-995
[2]   Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis [J].
Criddle, DN ;
Murphy, J ;
Fistetto, G ;
Barrow, S ;
Tepikin, AV ;
Neoptolemos, JP ;
Sutton, R ;
Petersen, OH .
GASTROENTEROLOGY, 2006, 130 (03) :781-793
[3]   Genetic testing for hereditary pancreatitis: Guidelines for indications, counselling, consent and privacy issues [J].
Ellis, I ;
Lerch, MM ;
Whitcomb, DC .
PANCREATOLOGY, 2001, 1 (05) :405-415
[4]  
GALLAGHER S, 1981, GASTROENTEROLOGY, V80, P970
[5]   NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area [J].
Gerasimenko, JV ;
Sherwood, M ;
Tepikin, AV ;
Petersen, OH ;
Gerasimenko, OV .
JOURNAL OF CELL SCIENCE, 2006, 119 (02) :226-238
[6]   Alcohol and zymogen activation in the pancreatic acinar cell [J].
Gorelick, FS .
PANCREAS, 2003, 27 (04) :305-310
[7]   Ciclosporin aggravates tissue damage in ischemia reperfusion-induced acute pancreatitis [J].
Hackert, Thilo ;
Pfeil, Dagmar ;
Hartwig, Werner ;
Fritz, Stefan ;
Gebhard, Martha-Maria ;
Klar, Ernst ;
Werner, Jens .
PANCREAS, 2006, 32 (02) :145-151
[8]   Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis [J].
Halangk, W ;
Lerch, MM ;
Brandt-Nedelev, B ;
Roth, W ;
Ruthenbuerger, M ;
Reinheckel, T ;
Domschke, W ;
Lippert, H ;
Peters, C ;
Deussing, J .
JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (06) :773-781
[9]   Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation [J].
Halangk, W ;
Krüger, B ;
Ruthenbürger, M ;
Stürzebecher, J ;
Albrecht, E ;
Lippert, H ;
Lerch, MM .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2002, 282 (02) :G367-G374
[10]   A unique pancreatic mitochondrial response to calcium and its role in apoptosis [J].
Halangk, Walter ;
Lerch, Markus M. .
GUT, 2009, 58 (03) :328-330
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