Outcomes among patients treated for gastric adenocarcinoma during the last decade

被引:9
作者
Bringeland, E. A. [1 ]
Wasmuth, H. H. [1 ]
Johnsen, G. [1 ]
Johnsen, T. B. [1 ]
Juel, I. S. [1 ]
Mjones, P. [2 ]
Uggen, P. E. [1 ]
Ystgaard, B. [1 ]
Gronbech, J. E. [1 ,3 ]
机构
[1] Univ Trondheim Hosp, St Olavs Hosp, Dept Gastrointestinal Surg, N-7006 Trondheim, Norway
[2] Univ Trondheim Hosp, St Olavs Hosp, Dept Pathol, N-7006 Trondheim, Norway
[3] Norwegian Univ Sci & Technol, Dept Canc Res & Mol Med, N-7034 Trondheim, Norway
关键词
gastric cancer; gastric resections; mortality; chemotherapy; palliative surgery; survival; PERIOPERATIVE CHEMOTHERAPY; NEOADJUVANT CHEMOTHERAPY; HOSPITAL VOLUME; D-2; RESECTIONS; SURGICAL TRIAL; CANCER; SURGERY; SURVIVAL; MORTALITY; STOMACH;
D O I
10.1002/jso.23320
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objectives To evaluate the outcomes among patients treated for gastric adenocarcinoma in a referral hospital, and to identify possible trends during the last decade. Methods All patients evaluated for gastric adenocarcinoma during the period 19992009 were included. Results Of 397 patients, 52% were curatively resected. Crude 5-year survival for the first 6 years period was 38.7% (CI 29.547.9), for the last 5 years, 49.2% (CI 38.859.6). Time period (P=0.013), age (P<0.001) and disease stage (P<0.001), were significant predictors of long-term survival rates. Among curatively resected, in-hospital mortality was reduced from 8.5% in the first period to 2.0% in the last one (P=0.037). There was a significant increase in the use of primary stents from the first to the last period (P=0.006), paralleled by a significant reduction in the number of explorative laparotomies or bypass procedures (P<0.001). Conclusions During the last decade, long-term survival rates improved among patients curatively resected for gastric adenocarcinoma, and in-hospital mortality was substantially reduced. For patients in a non-curative situation, there was a significant shift from explorative laparotomies or bypass procedures to primary use of stents. J. Surg. Oncol. 2013;107:752757. (c) 2013 Wiley Periodicals, Inc.
引用
收藏
页码:752 / 757
页数:6
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