MR-based trabecular bone microstructure is not altered in subjects with indolent systemic mastocytosis

被引：2

作者：

Baum, Thomas ^{[1
]}

Karampinos, Dimitrios C. ^{[1
]}

Brockow, Knut ^{[2
]}

Seifert-Klauss, Vanadin ^{[3
]}

Jungmann, Pia M. ^{[1
]}

Biedermann, Tilo ^{[2
]}

Rummeny, Ernst J. ^{[1
]}

Bauer, Jan S. ^{[4
]}

Mueller, Dirk ^{[1
,5
]}

机构：

[1] Tech Univ Munich, Klinikum Rechts Isar, Inst Radiol, D-81675 Munich, Germany

[2] Tech Univ Munich, Klinikum Rechts Isar, Klin Dermatol & Allergol Biederstein, D-80802 Munich, Germany

[3] Tech Univ Munich, Klinikum Rechts Isar, Frauenklin & Poliklin, D-81675 Munich, Germany

[4] Tech Univ Munich, Klinikum Rechts Isar, Abt Neuroradiol, D-81675 Munich, Germany

[5] Univ Klinikum Koln, Inst & Poliklin Diagnost Radiol, D-50937 Cologne, Germany

来源：

CLINICAL IMAGING | 2015年 / 39卷 / 05期

关键词：

Indolent systemic mastocytosis; Osteoporosis; Magnetic resonance imaging; Trabecular bone microstructure; DISTAL RADIUS; MINERAL DENSITY; OSTEOPOROSIS; FRACTURES; STANDARDIZATION; ARCHITECTURE; DIAGNOSTICS;

D O I：

10.1016/j.clinimag.2014.12.006

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Subjects with indolent systemic mastocytosis (ISM) have an increased risk for osteoporosis. It has been demonstrated that trabecular bone microstructure analysis improves the prediction of bone strength beyond dual-energy X-ray absorptiometry-based bone mineral density. The purpose of this study was to obtain Magnetic Resonance (MR)-based trabecular bone microstructure parameters as advanced imaging biomarkers in subjects with ISM (n=18) and compare them with those of normal controls (n=18). Trabecular bone microstructure parameters were not significantly (P>.05) different between subjects with ISM and controls. These findings revealed important pathophysiological information about ISM-associated osteoporosis and may limit the use of trabecular bone microstructure analysis in this clinical setting. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：886 / 889

页数：4

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